r/Biohackers

Best things to take for fat loss? I’ve already changed my diet and I exercise daily but I’m not losing weight.

i see people taking 5-10 supplements a day.

i always believed that we can get almost all nutrients from a balanced diet. maybe except vitaminD.

so which supplements would you say everyone should pick for life ?

It can be so frustrating trying to eat healthy only to end up looking six months pregnant twenty minutes later. I can eat a warm bowl of spiced rice with butter and feel completely flat and comfortable, but the moment I eat a plate of steamed cauliflower, broccoli, or cabbage, my lower stomach feels like an overinflated balloon. It makes you feel like you are doing everything right on paper while your gut completely disagrees. Which supposedly safe vegetables set your bloating off the hardest?

This is my biggest challenge and I'd love to hear some out of the box way that help that aren't melatonin, less light at bedtime, and things commonly recommended. Thank you!

How's it going, idk how else to start but anyway.

I'm a 21 y/o male, and I have a girlfriend. My sex life has always been something I've taken pride in, really just because I enjoy satisfying my partner. Recently (kind of as of last year maybe the middle of 2025) my erections haven't been as full or as strong as they used to be when I was younger (in high school).

Won't sugarcoat it though I've looked at some sort of pornographic material and I used to never have an issue being hard or staying hard before, during, or even after masturbating or sex but recently I don't know what's changed at least since last year. There would be times I would be with previous partners, and we'd have to stop because they couldn't keep going and I wouldn't finish or I would and would be able to keep going anyway. Regardless of that it's always been something me and them would talk about and make sure everything was okay (mentally and physically wise).

I guess my main concern is if something is wrong with me, I wasn't a "fit" guy either, I used to be 250+ pounds at 6'1, would rarely workout and slept and ate like I had nothing else to do. As of now, I'm out of the military and stay pretty active, lifting at least 5-6 times a week and get my cardio in daily. sleep is here and there with how many hours studies say we should get. I want to say that around the time I realized my erections were at their peak was before I knew about certain supplements like zinc, l arginine, lecithin granules and maybe one or two other things I used to take and I did notice a change but I didn't take them as much after a while and still felt the fullness that I used to have. I haven't taken anything like it for about two-ish years, and it has been a concerning amount of time since my last rock-hard erection. I'm not as adamant about it now as I used to be just because sex isn't something I'm truly concerned with but I'd like to be able to feel myself when I wake up in the morning or randomly get a boner like I used to and feel somewhat uncomfortable in my own clothes. (And I mean that in the most non-weird way as I possibly can.)

Advice is definitely wanted.

Its getting slowly colder and im loosing my tan sadly.
Do you know something which works great? i cant take astaxanthin because of my migraines.

I saw a post about a study done on women who took escitalopram antidepressants, where half of them were also given 5mg of creatine monohydrate, and those participants saw significant improvement within two weeks for depression symptoms, and continued to see improvements 8 weeks into the study as well.

As a depressed 33f woman I am intrigued and interested in it. But have no clue where to start. Any brand recommendations? Is it powder only or is it a pill form? Do I HAVE to workout right after taking creatine or will I be ok not to? Anything else you know about it lmk! I’m intrigued and just gathering some intel before making any purchases.

My goodness gracious, this exploded my strength, stamina and cognitive capacity. It’s truly remarkable. No other natural-product has ever worked this great for me other than cafeïne, but that comes with a lot of negatives.

What has your experience been with creatine?

im 6’0” weight 175lbs. atarted taking meth recently.

never felt good off any dose of meth just a little more locked on, why does this happen, ive took like a .2 w no tolerance at all and just felt speedy. I get good icy clear not no cut bullshit that I tested. Can smb pls tell me why, I just use it like adderall but even adderall makes me feel better than meth at high doses. Please tell me why, im not mad tho if anything its a blessing cuz I don’t wanna be a homeless tweaker bum itching for the next hit I function perfectly and take tolerance breaks too.

I'm 26M. Spent 2–3 years obsessively working on my businesses, and it paid off. I was extremely driven, focused, and could work endlessly. No nootropics or medications, just coffee and nicotine.

Eventually I decided to slow down and take a break after years of pushing myself, but ever since it's been a downward spiral.

The weird thing is I actually feel mentally sharper than before. I come up with better ideas, spot opportunities, solve complex problems and know exactly what needs to be done.

But my execution has gone to shit.

And this isn't just a temporary phase. I've been stuck in this exact loop for almost 2 years now. Every time I tell myself I'm finally going to get back on track, I end up repeating the same pattern. It's exhausting because I know what I'm capable of, but I can't seem to get back to the version of myself that used to execute relentlessly.

I've left so many things unresolved that they've stacked up. Whenever I sit down to work, I get overwhelmed by everything that needs doing. I'll start one task, notice something else, jump into that, discover another problem, and eventually get completely lost. Then I just want to stop working and chill, even though I genuinely want to get things done.

Another thing is how easily irritated I've become. I'm not naturally an angry or stressed person, but lately even people asking me simple questions can piss me off. My head is already full of responsibilities, opportunities I'm not acting on, and frustration about being stuck in this unproductive loop.

Sometimes I wonder if success made me too comfortable, but honestly I don't feel comfortable at all. I feel constantly pressured by everything I'm not doing.

For context, I consume quite a lot of nicotine daily through vaping and cigarettes, plus around 3 espressos a day. I've never really been into drugs or nootropics. Used to smoke weed years ago but quit, nowadays maybe once a year at most.

I recently tried L-theanine for stress. It seemed to help a little, but nothing significant. I also noticed some acid reflux, although I'm not sure whether it was caused by the L-theanine or was just a coincidence, so I stopped taking it.

Now I'm considering bromantane. I have a 90 mg/mL nasal spray and was thinking of using one spray in each nostril, although I haven't started and don't know the actual dose delivered per spray. I've also seen people mention combining bromantane with L-tyrosine, but I'm unsure whether that's beneficial or even advisable.

I don't want to become dependent on anything. I just want to regain the focus, discipline and execution I naturally had before.

Has anyone experienced something similar after years of intense work? Did bromantane actually help with execution, task switching and mental overwhelm, or did it just make you feel more stimulated?

Would you combine it with L-tyrosine or avoid that? And what about long-term effects on natural motivation, dopamine, libido, emotional blunting, tolerance and how you feel after stopping?

Would appreciate genuine experiences, good or bad. I'm also open to hearing that bromantane isn't the answer and that I should be addressing something else entirely.

Disclaimer: Not looking for medical advice, just personal experiences and research. I understand bromantane has limited human safety data, especially when used intranasally, and I'll consult a healthcare professional before making any decisions.

What Calorie Counter Do You Use?

Barefoot. Arms at my sides. Eyes forward.

Ten seconds on the left, ten seconds on the right.

I am not doing it as a leg-strength workout.

It’s a small, repeatable balance check.

My left side has always been worse by about two seconds.

That is just enough to give me a baseline.

What I actually record

I note:

- which leg I used

- roughly how long I held it

- whether I touched the counter

- whether I was barefoot or wearing shoes

- whether I felt dizzy, weak, or in pain

- whether one side was consistently different.

I keep the conditions roughly the same: same surface, eyes open, counter nearby, left side and then right side.

If I’m worse after a terrible night of sleep, I make a note of it. If I’m worse for weeks, I pay more attention.

I am interested in whether a change persists under the same conditions, not in winning a ten-second challenge.

I just like repeatable observations and apparently enjoy turning ordinary activities into tiny personal experiments.

My balance has improved, did it also help my mind balance more? I think so.

=====================

The study that started it

I started after reading a 2022 study of 1,702 adults aged 51 to 75. The researchers tested whether people could complete a 10-second, unsupported one-leg stance. 20.4% of the participants could not complete it.

At a median follow-up of seven years, 17.5% of the people who could not complete the stance had died, compared with 4.6% of those who could. After adjustment for age, sex, body mass index, and several health conditions, inability to complete the stance was associated with an adjusted hazard ratio of 1.84 for death from any cause.

That is the source of the often-quoted “84% higher risk” figure. [The study is here.](https://pubmed.ncbi.nlm.nih.gov/35728834/)

That sounds dramatic, but it needs context. This was an observational association in one group of adults. It does not mean that if you have poor balance you are going to die and that poor balance caused those deaths.

A poor result may reflect more than leg strength.

The study used one standardized test in one age group.

Why balance is more than leg strength

Staying upright uses information from your vision, inner ears, feet and joints, muscles, spinal cord, and brain. Those systems have to work together quickly enough to keep you from tipping over.

One term I learned while trying to understand why my left and right sides differ was proprioception.

It means knowing where your body is and how it is moving without looking at it.

Close your eyes and touch your nose: you know where your hand is because your nervous system is tracking the position of your arm and fingers.

The first time I tried the one-leg version with my eyes closed, I grabbed the counter almost immediately. It was not graceful. Removing vision showed me how much information I had been using without noticing.

That is also why I stopped calling my routine a Romberg test.

A classic Romberg examination usually has a person stand with both feet together, first with the eyes open and then with the eyes closed, while a trained examiner stays close.

The NCBI overview explains the distinction and the safety requirements.(https://www.ncbi.nlm.nih.gov/books/NBK563187/)

Some people seem to go by whether they actually feel a difference, others are fine relying on the research or a measurable change. Where do you draw the line? Have you ever stopped one because you couldn't tell if it was worth the money? Not looking for recommendations or medical advice, just curious how people make that call.

Has there been any studies with peptides to help slow it down ?

What’s your thoughts on this disease, ways to combat it prevent it ?

Not caused by excessive smartphone usage or chronic binging of any food or activity. I’m actually an applied math undergrad and have been dealing with this issue for several years. Being constantly under stimulated and distracted. I know my trouble is focus not intel. It’s getting worse, however. I’m now constantly picking my beard or grinding my teeth, trying to fulfill any craving for dopamine. Even when I exercise, eat bland, read boring things, I just cannot meet my stimulation needs. I was Rxd Vyvanse and it actually helps but it feels like a patch. I tried some methylated vitamins which helped give me more methyl donors to promote dopamine levels. That also somewhat helped but still a patch. I tried sativa THC for the first time a few weeks ago and I was incredibly wired and it felt like pure ❄️. Maybe this is a GABA/Glutamate thing? I took some L theanine for the first time with Vyvanse and it was really helpful! Less stimmy and more focused. But maybe that hints at gaba and glutamate signaling. Not to mention I had an absolutely uncontrollable addiction to nicotine and quit a few years ago, so now I just supplement CDP choline and b9 and those cravings are poof gone. But man, THC just like activated something that I’d never felt, not in the psychoactive novelty seeking way, but in the sense of smooth and undistracted thinking. The dopamine boost from THC is so little in comparison to Vyvanse, so I thought that the THC was engaging some other mechanism that completely took away my chronic stimulation needs for a few hours.
I know it’s largely dopamine related in some way or another because a huge Vyvanse dose puts my brain to complete zen mode no hyperactivity no tooth grinding or face picking. But how is it that THC produced basically equivalent results when the dopamine boosting affect of THC is so minor compared to amphetamine.
I’ve supported by Choline pathways with CDP choline which helped take the load off of my Slow COMT, treated my (minor) b9 and b12 deficiency (basically had burning and tingling hands and feet constantly and was always exhausted), and I get in the right amount of cardio, electrolytes, hydration, whatever you can possibly do. What am I missing? Why did 1 thc puff feel like it fixed my chronically under stimulated brain and made me super productive, when Vyvanse can barely do so at a substantial dose. Am I missing something or is something just wrong with my brain?

Testosterone			900		ng/dL
Testosterone Free Calculated			217.7		pg/mL
Testosterone Bioavailable Calculated			17.7		nmol/L

I also believe there is something to be said for living long enough to experience trauma/grief/stress, that directly impact the body. I was always tiny and lightweight. After a huge trauma last year i developed back rolls and gained 10-15 pounds that do not budge.

I walk, do bodyweight exercises, dance, and stretch/deep breathe to relieve some stress. Do I now have to become a drill sergeant to myself about going to the gym?:') maybe getting into a calorie deficit?

I hear these things all the time: you're just getting older, it's what happens to everyone. I don't want to accept that and that most likely means making lifestyle changes even though I got by fine before without having an intense approach.

Would love to hear your advice and experiences?

I love coffee, but I noticed even a small cup after lunch affected my sleep. I switched to a noon cutoff for the past 10 days.

Sleep latency seems better so far. Curious what cutoff time works for other people.