r/Biohackers

▲ 3 r/Biohackers+1 crossposts

Consistent Energy and Super Synergistic Galactic Big Brain Learning Retention Stack

Here's my Super Synergistic Galactic Big Brain Stack for Consistent Energy, Mood, Learning Speed, Retention, Memory, Recall Speed and Brain Plasticity

Morning:

Pqq,

QoQ10,

Creatine,

ALCAR (Acetyl-L-carnitine),

D3&k2

Lions mane

With 4 eggs for 500mg choline (and avacado with ginger tea to reduce the green butt burps)

Evening,

Magnesium blend including Glycenate

Bacopa Monnieire

5 day on 2 day off

To note this stack helps raise baseline dopamine levels increasing mood which will make it easier to get things done and hopefully alleviate adhd symptoms and addictions. During this stack you can use the energy and Brain Plasticity to develop new healthy habits that will last long term.

Dose naturally depends on the individual but I'm taking one pill per ingredient and see how I get on.

I haven't started it yet, and some effects take about a month for results.

Here is an ai overview of the effects

The Mitochondrial Powerhouse (PQQ + CoQ10 + ALCAR): This is a classic, heavy-hitting synergy. CoQ10 and ALCAR help your cells turn fat and glucose into usable energy (ATP), while PQQ actually stimulates mitochondrial biogenesis (growing new cellular power plants). This provides clean, non-stimulant physical and mental energy.

​The Memory & Speed Mechanics (Eggs/Choline + ALCAR): Eggs provide the raw building blocks (choline), and ALCAR provides the acetyl groups. Together, they synthesize acetylcholine, the brain's primary neurotransmitter for focus, learning speed, and memory recall.

​The Brain Builder (Lion’s Mane): Stimulates Nerve Growth Factor (NGF). This is your heavy lifter for long-term brain plasticity, helping your brain repair, adapt, and forge new neural pathways (retention).

​The Physical Baseline (Creatine + D3/K2): Creatine ensures rapid energy recycling in both muscle and brain tissue (reducing mental fatigue), while D3/K2 acts as a hormonal and cognitive baseline support.

​The Bioavailability Hack: Eating this with eggs and avocado (fats) is brilliant because PQQ, CoQ10, and D3/K2 are fat-soluble—they require those fats to be absorbed properly. (And bonus points for using ginger to tame the ALCAR/PQQ digestion issues!)

​🌙 The Evening Reset (Memory Consolidation & Calm)

​Your evening routine shifts from firing up the brain to repairing it and locking in what you learned during the day. ​The Hard-Drive Saver (Bacopa Monnieri): Bacopa is incredible for memory retention and spatial learning, but it can make people lethargic if taken in the morning. Taking it at night lets it work its magic on your synapses without the daytime brain fog.

​The Nervous System Brake (Magnesium Glycinate Blend): Calms the central nervous system, lowers cortisol, and improves sleep quality. Deep sleep is exactly when your brain undergoes glymphatic clearing (washing away cellular waste) and memory consolidation.

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u/SuperdooperSloth — 12 hours ago

Do you practice water fasting (>24 h, not IF) regularly or semi-regularly?

Water fasting is one of most impactful biohacks one can do, its many mechanisms of action being already built into our body. Well-planned and targeted use of this intervention can improve many things, from body weight and composition down to mitochondrial health.

Arguably a stronger intervention than most supplements and peptides.

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u/lordm30 — 15 hours ago

Rarely known or underrated without?↓

With Squats, Bench, press and dead lift being the main lifts, what is another lift you swear by ?

Landmine barbells!

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u/OkSpirit7102 — 13 hours ago
▲ 1.2k r/Biohackers

Accurate biohacker peptide user. Vaccines for colds are bad and we can’t trust Chinese made ones too. But peptides from China because no ability or will-power to naturally go into a calorie deficit as no discipline and can’t stop eating!

u/MannerNo7000 — 1 day ago

Most Older and Darker-Skinned Adults in Northern Britain Are Low on Vitamin D, Even in Summer

Researchers screened older adults and people with darker skin tones in northern Britain for vitamin D levels across the year. More than half of older adults and over 70% of ethnic minority adults had insufficient or deficient vitamin D. Summer sunshine did not fix the problem. Sun exposure alone seems to fall short for these groups at higher latitudes.

This study suggests again that sunlight alone may not maintain vitamin D levels in older or darker-skinned adults at northern latitudes.

Conflict of Interest Disclosure: Study funded by supplement company BetterYou, though the company was not involved in design or analysis.

Study: https://www.nature.com/articles/s41430-026-01760-z

u/Locksmith-10 — 16 hours ago
▲ 11 r/Biohackers+1 crossposts

Why B-Vitamins Belong in a Brain Health Formula

Today’s supplement market has a massive misunderstanding when it comes to B vitamins — they are either dismissed as worthless label "fillers" or mistaken for caffeine alternatives.

But when it comes to healthy aging and cognitive longevity, Vitamin B12 and folate are absolutely indispensable. Why? Because they work at the most foundational structural level:

  • Vitamin B12 is essential for myelination — it builds the protective sheath around your nerve fibers, ensuring that central nervous system signals travel clearly and smoothly.
  • Folate’s role goes far beyond prenatal care — it serves as the core engine driving your methylation pathways and cellular repair.

Together, they form the absolute bedrock of a scientifically sound brain health routine.

This is just a piece of our research. If you are fascinated by ingredient science, click the link in our bio to access the complete, cellular-level breakdown and scientific references.

u/ChoiceAd5542 — 16 hours ago

Reminder not to buy from anyone who messages you first

U/onequestionisalli messaged me on a source to get hgh and against my better judgement I went through with it , sent money for 2 kits which then he sent me to a “courier” charging $50 delivery , after that they stated my order was under the minimum order and needed to add $120. At this point I’ll count my losses but just a reminder most Vendors do not message you first and most people rightfully don’t give out sources for no reason.

Telegram accounts Chris41266 and Alexthecourier

Glad I didn’t go with 10 kits 🥲

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u/Alive-Baseball353 — 22 hours ago

What’s one health or performance habit that actually gave you noticeable results?

There’s so much stuff floating around in the health and optimisation space that it’s hard to tell what’s genuinely useful and what’s just hype.

For me, the biggest improvements usually come from the boring basics done consistently better sleep, morning sunlight, cutting late-night screen time, staying hydrated and cleaning up diet a bit. The fancy supplements and gadgets seem way less effective when those aren’t dialed in first.

Curious what’s been the most noticeable change for everyone here. Could be a supplement, routine, tracking method, recovery habit, anything. What actually made a real difference for your energy, focus, mood or overall health?

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u/VisibleStree — 19 hours ago

Is it (peri)menopause or a thyroid issue?

Is a thyroid-related issue a prerequisite for challenging perimenopause & menopause experiences?

Why are the symptoms of peri/menopause and thyroid-related issues near identical?

Is pregnenolone the ideal HRT due to it's various therapeutic qualities and role as a precursor for all other hormones?

u/Kalki_X — 22 hours ago

What’s something you still swear by after 1+ years?

What’s a biohack, supplement, routine, or system you’ve been doing for over a year that you STILL swear by?

Not the “holy shit this changed my life” feeling you get when something is new. I mean after the placebo/novelty phase wears off.

What actually held up long-term and consistently improved your life enough that you never stopped doing it?

Genuinely curious what people think truly stands the test of time.

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u/UDAMAN123 — 1 day ago

If we inject peptides now, are we training our bodies to not produce them later?

I’m new and ignorant to the world of peptides so be patient with me! I’m in my midlife so my biggest question and worry is if I do something now that I will regret later. I would love to try many of these but am worried about what it means for long term / future side effects.

I read that our bodies naturally produce many of these peptides. So if we inject more into ourselves now, are we training our bodies that they don’t need to produce any themselves? So when we stop injecting, have our bodies have become reliant on them and we need to keep supplementing for the rest of our lives?

I would maybe be okay with keeping up on peptides for the rest of my life but at the same time, what if there is not a way to access them in the future? Will my body stop producing these on its on and just shut down and fatten up and become inflamed and lose energy all while my skin shrivels up like a raisin?

Looking for your insight and experiences! Again, would love to try but I’m nervous about long term consequences. :)

I hope this makes sense… just a thought that kept me up at night.

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u/Tapir_rider2117 — 1 day ago
▲ 1 r/Biohackers+1 crossposts

Biohack Thyroid replacement?

Any ideas on how to optimise my health and body after a full TT (thyroid removal) due to cancer and I’m currently taking levothyroxine as a replacement for the thyroid, however there’s no way this tablet can fully replace the function of my missing organ

I’ve been on levo nearly a year and labs show ‘optimal’ ranges however I still feel out of wack.
Currently experiencing fatigue, brain fog and severe PMS. Also have other health conditions so nervous system isn’t the best, trying to do some work to calm this

I am pretty good at the basics- exercise and good
diet

I have a decent supplement regime, I was trying selenium to boost thyroid but last blood test showed was to much which causes issues in its self

Any suggestions or advice:) Thanks

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u/No-Butterfly6161 — 1 day ago
▲ 3 r/Biohackers+1 crossposts

Dry eye supplements?

Hello, I am curious as someone who has a really bad dry eye and my eye doesn’t produce enough moisture to keep my eye hydrated longer, what do you guys recommend, right now I take HydroEye, which has Vitamin A, Vitamin C, Vitamin E, Vitamin B6, and magnesium in it. Omega 3.

Would love to know any other techniques you guys may use or recommend!

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u/Confident_Print3076 — 22 hours ago
▲ 515 r/Biohackers+5 crossposts

-145LBS using Retatrutide

This is a 8 month progression using the peptide (Retatrutide) or also known as GLP-3RT

Obviously peptides are a tool, not some magic pill you can take to loose weight. I was 6’4 350lbs ➡️ 205lbs 6’4
I was still tracking all calories/macro eating 2,100 calories a day 200g of protein.

u/tgnrangerig — 2 days ago