In low and sparse enough doses, can *any* pyrros or caths be used as ADHD treatments? Or is a beta-ketone an automatic "too peripherally dangerous and too addictive" write-off for a compound to be feasible for functionality?
My go-to stimulants for ADHD have always been IPPH and 4F-MPH, I'm living in a country in which the waiting list for a proper pharma script is loooooong (like, several years long) so while I'm already on that list, I've needed to self-medicate. Believe me, I have tried to get a pharma MPH script and probably will in about two years 😂
As everyone knows, these stims literally vanished from the EU market after near-simultaneous bans in China and NL; and currently the only widely marketed stims are caths (notably the CMCs and MMCs) - which seem likely to also dry up relatively soon because of a recent EU initiative to restrict their precursors - and pyrros, which I don't know if will be similarly impacted by the aforementioned upcoming restrictions.
I'm wary of anything in the cathinone family because there are so, SO many stories here (and in published literature) of people losing control and falling down an addiction rabbit hole, and because there have been high-profile, legitimate reports of these compounds killing people when misused. That beta-ketone seems to add a dangerous edge to more or less any phenethylamine - even prescribed ones like Buproprion are known to have dangerous side effects relating to seizures, hence the longstanding issues in medicine around balancing theraputic doses vs safe doses for that.
With all this in mind; currently MDPHP, 2-CMC, 2-MMC, and several PiHPs (2-Me-PiHP, 3F-PiHP, and MDPiHP) seem to be the only ones currently being produced on a large scale for the EU. Would any of these potentially be of use for ADHD self-medication, or is the risk of addiction and serious harm simply too high to make it worth chancing?
Ultimately, all of these drugs are still simply monoamine releasing agents or reuptake inhibitors, the only differences between them really being in what proportions and how rapidly these monoamines accumulate, and the central vs peripheral stimulation ratio. This would seem to logically suggest that any of them could be used functionally, and that its only the dosage which would tip the balance between safe and dangerous / addictive - after all, even regular meth is used as a prescription drug, just in a very low 5mg daily dose as opposed to the high doses used by recreational users.
However, this just doesn't seem to be the case - right across the world of phenethylamines, it seems that a beta-ketone takes any "safe" (relatively) compound, and pushes it over the line into "hyper-addictive, more peripheral side effects, and definitely not something to try if you're looking for functionality and not just a party drug".
Essentially, for functional (ADHD-relieving) and semi-regular use (2/3 days per week), are caths and pyrros worth considering dabbling in? Or is my gut instinct (beta-ketone present = not worth risking for functional use) the right one?
I'm very good at resisting redosing with the stims I currently use - a single 15mg or 25mg pellet of 4F-MPH for example is my absolute daily limit on the days I take it and I've never gone over this line, even after about a year of regular use. So I do have some self-control when it comes to stims, even this limitation of not redosing seems to be something many people really struggle with, I seem to be quite lucky in this regard. But at the same time, everything I've read about caths and pyrros seems to suggest that dabbling would be tempting fate.
Any thoughts or experiences to share? Anyone ever try this, and how did it go for you? Anyone start off with similarly functional intentions and get sucked into the compulsive bingeing rabbit hole, or have any of you succeeded in using caths / pyrros in a controlled and sustainable manner?