Anyone know if there's a test for non-reactiveness yet?
I know from reading various posts and studies online that there's approx 9-15% of people are supposedly non-responders to GLP1 antagonists like Semaglutide and Tirzepatide. But, does anyone know if there is a definitive test people can take to confirm this diagnosis yet or not?
For added context, I was previously on 15mg Mounjaro after titrating up which took just over a year ish because I had excruciating side effects every time I stepped up (including 3am calls with on-call doctors and hospital visits because of the pain).
I stopped taking Mounjaro when the prices spiked up September 2025. I couldn't afford it and at the time my weight loss had plateaued despite tightly controlling my calorie intake and doing heavy 3hr gym sessions 3 days a week (full body workouts + Cardio + Swimming).
I started at just over 200kg in Dec 2023 and started dieting and working out then.
I started taking Mounjaro at 187.6kg towards the end of July 2024.
August 2025 - Sept 2025 (when i stopped the jabs) I was fluctuating weekly around 165kg with my lowest weigh-in being 163.8kg
From Sept 2025 - Jan 2026 I continued to float around the 165kg mark.
Feb 2026 there was a fire that shut my gym down for a couple months and I fell off the wagon, stopped tracking food, stopped gymming, started playing world of warcraft again because of the nostalgia and fomo from a new expac and I'm now back up to 180Kg and sick of my own weaknesses.
SO, I started taking WeGovy 11 weeks ago, currently on the 1mg dosage and I've not lost any weight at all in this time, over the 11 weeks I’ve stayed exactly at 180.0kg. I've not been feeling any of the usual effects from the drug at all, no reduction in appetite, obviously no weight loss, nothing..
I'm supposed to titrate up again to the next dose of wegovy but I'm starting to lose hope again and questioning whether there's any actual fucking point to doing this and spending all this money if im not reacting to it at all.
So yeah,
TLDR: knowing for definite if I’m a non-responder or not would be great. so, anybody heard anything about testing being available and accurate?