Chronic GBS UTI + penicillin allergy
Hello, I’m really hoping someone can offer some insight. I feel like I’ve hit a brick wall here and I’m miserable.
I’m 31(FTM) and am with a cis male partner. We’ve been together a year. I got Group B Streptococcus (GBS) sepsis in Oct 2025 and was on IV clindamycin for the first three days, then on IV rocephin for two months. They attributed it to cellulitis, but now I’m thinking it was a UTI. Urine culture showed strep b and mixed flora positive.
It was a rough recovery but I finally got better with some lasting effects. Fast forward to May 17th and I go to urgent care with straight blood in my urine and some lower abdominal pain and cramping. Culture came back positive for klebsiella pneumonae, GBS, and mixed flora. They gave me 2g rocephin IV and sent me home on cephalexin.
June 4th, I go in for a recheck cuz I’m not quite feeling 100%. Culture shows I’m still positive for GBS and it has increased in severity. Doc only prescribed phenazopyridine which I didn’t take.
June 30th shows increased colonization of GBS in my urine and I’m feeling a bit hopeless by this point. They prescribe ampicillin but I declined picking it up because I’m ALLERGIC to penicillins. Apparently I get rashes and have only taken it as a baby. They tell me it’s my only choice besides a single IM injection of 2g rocephin. So I get the injection and pray it works even though I know it won’t.
Sure enough, it’s been five days and I’m feeling worse. My symptoms essentially are fatigue, back pain, lower abdominal heaviness and cramping. Do I just take the thing I’m allergic to?? What if I go into anaphylaxis? I’m afraid of becoming septic again and the possibility of this being resistant to rocephin.
Any help is greatly appreciated.