Anyone progressed to IVF + PGT-A after TFMR? Looking for experiences and hope at 42 after three losses
Hi everyone,
I recently underwent a medical TFMR at <17 weeks after our baby was diagnosed with T21 with rapidly developed severe hydrops and was unlikely to have survived much longer in pregnancy.
42.5 yo previously had a MMC and chemical pregnancy. All pregnancies were conceived naturally, including the last one we had to TFMR.
We cannot go through this hardship again, stopped naturally ttc to minimise the risk of another chromosomal loss and moved forward with IVF + ICSI + PGT-A.
Our last pregnancy was conceived through ovulation induction, so I am somewhat familiar with IVF stims protocols already.
Following TFMR, my consultant advised:
Period #1 after TFMR → begin Genotropin (HGH) + prenatal supplements
Period #2 after TFMR → start IVF/ICSI stimulation medications for egg collection and embryo creation
I will proceed with frozen embryo transfer only once hormones and my body had recovered appropriately after TFMR/stimulation and we have a euploid.
I’ve already started Genotropin and supplements and would really appreciate hearing from others who moved to IVF after TFMR, especially recurrent loss in your 40s.
- How long after TFMR did you begin IVF treatment?
- Did your doctor recommend waiting a certain amount of time before stims/transfer?
- How many retrievals did it take to get euploid embryos?
- How long did it take for your cycle and hormones to normalise after medical TFMR?
- Did IVF after TFMR eventually lead to your rainbow baby?
I know realistically that time is not on my side anymore. After staggered losses, your backbone grows stronger because it has to. I had to look beyond this devastating chapter and keep moving toward some hope, otherwise it would have been very easy to give up and accept that I may never become a earthside mother.
Thank you to anyone willing to share their experience, and I am so sorry for what we all have gone through 🤍