u/Illustrious-Exit-474

I need to know if I’m overthinking and/or spiraling for nothing…

3 FETs with euploid embryos all with no implantation and various regimens from fully medicated to modified natural, kitchen sink protocol, etc. November 2025 we did a mock cycle with EMMA/ALICE/ERA/receptiva testing. ERA showed receptive and EMMA/ALICE was normal. The Receptiva came back positive for BCL6 at 1.8 (reference range >=1.4), so our doctor recommended 2 months of Lupron Depot suppression with letrozole (+norethindrone for hormone add back therapy). So we did our first injection Feb 2026 and second March 2026.

After my second Lupron injection I messaged to find out FET timeline and what comes next and was told I was due for another saline infusion sonohysterogram (SIS) and could schedule my FET initial cycle visit for the week after finishing my last letrozole tablet. I was annoyed we couldn’t have done the SIS earlier but it was what it was. Long story short, I have the SIS completed end of April after they canceled an earlier SIS appt and OF COURSE they note a polyp in my uterus and recommend a hysteroscopy to remove it prior to FET. Due to the doctor’s schedule they couldn’t do anything in May and scheduled that for June 3rd.

They have me on no medications, nothing. The nurse messaged this week to ask if I was on norethindrone and when I’m expecting CD1 and I’m like you guys told me no meds and wtf I have no idea on CD1, I’ve been on suppression so nothing is predictable?! I’ve worked customer service so it takes a lot to get me riled up and I didn’t actually snap at her but gosh I was so upset reading that. I responded with a polite version and she said she just likes to check in and to let her know if I get a cycle but the Lupron suppression should cover me for the hysteroscopy. I’m losing trust with what feels like balls being dropped - does anyone know if I should be on anything?! Also panicking that we’re looking at a July transfer at the earliest now, 4 months after my last Lupron shot. Like did I just waste all the time and money spent on Lupron to not even get the benefits of it?!

This journey is so hard and now I’m just spiraling what feels like nonstop 😭

We started our IVF journey in July 2024 (no IUI) at age 34. Originally unexplained infertility (maybe still?). I previously had IUDs for like 8 years before we started TTC. Never have seen a positive test (except after trigger shots ha). We did an egg retrieval October 2024 and were blessed to end up with 6 euploid embryos after everything.

We’ve done 3 FET, all with no implantation. Our first (day 5 3BB) in December 2024 was a fully medicated transfer with vaginal estradiol and prometrium + PIO, our second in February 2025 (day 6 4BB) they added baby aspirin + immune protocol (prednisone, Claritin, Pepcid), and our third in May 2025 (day 6 4BB that fully hatched upon thaw) was a modified natural with endometrin instead of promethium and the kitchen sink (immune protocol + Lovenox and baby aspirin) with acupuncture.

In March 2025 between our 2nd and 3rd transfers we did a hysteroscopy for the first time (Dr found and removed a big polyp and some scarring on the back, no infection or endometritis) and an HSG for the first time (clear, no issues). She thought this was the issue for sure but then 3rd FET failed to implant.

Given our RIF and access to employer benefits we elected to do 2 more ERs the summer of 2025 to hopefully obtain some more embryos while younger vs if I got pregnant and needed to do more down the line. Our original doctor moved away and there were with a new doctor. The results with those ERs were not as strong as the first but we did get a total of 4 more euploids and a LLM.

November 2025 we did a mock cycle with EMMA/ALICE/ERA/receptiva testing. ERA showed receptive and EMMA/ALICE was normal. The Receptiva came back positive for BCL6 at 1.8 (reference range >=1.4), so our doctor recommended 2 months of Lupron Depot suppression with letrozole (+norethindrone for hormone add back therapy). So we did our first injection Feb 2026 and second March 2026.

After my second Lupron injection I messaged to find out timeline and what comes next and was told I was due for another saline infusion sonohysterogram (SIS) and could schedule my FET initial cycle visit for the week after finishing my last letrozole tablet. So I get my SIS scheduled and am planning for a May FET. The day of the SIS procedure I get called to reschedule due to a family emergency with the provider scheduled to do it. That was disappointing but life happens so we rescheduled for a week and a half later when my initial cycle visit was supposed to be, the RN said she would check about doing SIS and initial cycle visit same day. Then I get a message that their procedures for May were getting bumped because of the doctor’s schedule and we’d have to move to a June FET. This sent me spiraling because everything I’ve seen people talk about with suppression is going straight into transfer upon completion so I felt like I was losing out on benefits of the suppression. The nurse told me the suppression lasts for a while and not to worry.

Cut to today, I have my SIS and OF COURSE there is a polyp that comes upon. They are recommending a hysteroscopy to remove it prior to FET and so now we’re pushed back to July FET at the earliest. Feeling absolutely devastated and like a crazy person. My husband is furious and doesn’t understand why they didn’t do the SIS prior to Lupron suppression so we could take care of that and then do suppression straight into FET. I understand the suppression lasts a bit but my brain also goes to worst case scenario and if the first FET post-suppression doesn’t take we might not be able to squeeze in another with the effects in place because we won’t even be doing the first FET until almost 4 months after the last dose. It just feels like I did all this work with suppression and its side effects to not even be able to fully reap the potential benefits.

I don’t know what to ask my clinic. Or what to say to them. I feel so helpless and at the mercy of something I seem to have no control over. And I feel so let down by my clinic, kicking myself for not asking about SIS when discussing suppression but it never crossed my mind…so maybe I just failed myself. No one in our lives except my best friend knows we are doing IVF and she’s a mom of two small kids busy with her own life. So maybe this post is just looking for camaraderie and a space to talk. Any advice and/or experience also welcome. Thanks for reading if you made it this far ❤️‍🩹