5 Month Lab Comparison
I’m 60 yom that started my body transformation in January with a starting weight of 224 lbs., after visiting my PCP who wanted to place me on blood pressure meds. Concerned for my cardiovascular health and studying peptides I decided against BP meds and instead followed the following stack:
January 2026, 1mg micro dose Friday and Tuesday total 2mg weekly of Reta, 1mg daily 7x of Tesa
February 2026, 2mg micro dose 2x weekly of Reta, 2mg Tesa 7x week.
March 2026, 3mg micro dose 2x weekly of Reta, 2mg Tesa 7x week.
April 2026, 4mg micro dose of 2x weekly of Reta, 2mg Tesa 7x weekly, 1mg IPA 7x weekly, 3mcg MOTS-C 7x weekly, 3mcg BPC-187 7x weekly.
May 2026, 4 mg micro dose of 2x weekly of Reta, 2 mg Tesa 7x weekly, 1mg IPA 7x weekly, 1 mg MOTS-C 7x weekly, and 1mg BPC 187 7x weekly.
Now weigh 201 lbs.
Here are the before and after results; the stack works beautifully for me.
Lipid Panel Interpretation Summary
December 2026 - May 2026
Your December 2025 lipid panel compared to your current 2026 results shows a major metabolic improvement. The change is significant enough that it strongly suggests your current fasting, walking, Zone 2 cardio, resistance training, and weight-loss approach is working.
Side-by-Side Comparison
Marker
Dec 2025
Current
Change
Total Cholesterol
215
133
↓ 82
Triglycerides
263
76
↓ 187
HDL
42.1
44.1
↑ 2
LDL
120.3
73.7
↓ 46.6
Non-HDL
172.9
88.9
↓ 84
What These Changes Mean
Triglycerides: Massive Improvement
Your triglycerides dropped from:
263→76263 \rightarrow 76263→76
This is one of the most important changes in the entire panel.
A triglyceride level of 263 in December suggested:
• insulin resistance,
• excess liver fat production,
• higher metabolic risk,
• likely higher visceral fat burden.
Now at 76:
• your body is handling energy much more efficiently,
• insulin sensitivity has likely improved substantially,
• liver fat may have decreased,
• cardiovascular risk profile improved considerably.
This is exactly the type of shift commonly seen when:
• body fat decreases,
• fasting improves metabolic flexibility,
• sugar/refined carbohydrate exposure drops,
• aerobic conditioning improves.
LDL Cholesterol: Strong Improvement
Your LDL dropped from:
120.3→73.7120.3 \rightarrow 73.7120.3→73.7
That is a very meaningful improvement.
In December:
• LDL was still technically “acceptable,”
• but much less optimal metabolically.
Now:
• you are in a range many preventive cardiologists consider very favorable.
Non-HDL Cholesterol: Excellent Progress
Non-HDL fell dramatically:
172.9→88.9172.9 \rightarrow 88.9172.9→88.9
This is extremely encouraging because non-HDL captures nearly all potentially atherogenic particles.
Dropping below 100 is often viewed as excellent metabolic progress.
HDL: Stable to Slightly Better
HDL moved:
• 42.1 → 44.1
Not dramatic, but importantly:
• it did NOT fall while losing weight,
• and it slightly improved.
HDL often rises more slowly than triglycerides improve.
The Biggest Story: Your TG/HDL Ratio
December 2025 ratio:
This may be the clearest indicator of all.
Interpretation
• Above 5 → strong insulin resistance concern
• Around 3 → moderate concern
• Under 2 → very good metabolic health
• Near 1 → excellent
Moving from ~6.25 to ~1.72 is a dramatic improvement in metabolic status.
Overall Interpretation
Your December 2025 labs looked consistent with:
• metabolic dysfunction,
• insulin resistance,
• elevated cardiovascular risk,
• likely excess visceral fat/liver fat.
Your current labs now look consistent with:
• improving insulin sensitivity,
• substantially better metabolic flexibility,
• improved cardiovascular profile,
• successful body recomposition direction.
Combined with:
• your weight loss,
• lower triglycerides,
• better LDL,
• normal A1C,
• improved activity level,
this suggests your current routine is producing real physiologic improvement — not just scale weight changes.
This is one of the more impressive before-and-after lipid improvements you can achieve naturally in a relatively short period of time.
I pin Tesa and IPA evenings after 3 hour fast, I pin MOTS-C and BPC 187 AM fasted before morning 30
minute walk. Then another 30-45 minute walk after lunch both at Zone 2 cardio and light resistance training 3 x weekly around 40 minutes. Between 180-200g of protein daily, creatine, and electrolytes.