Titrating to 5mg got me really sick.
I started Zepbound about a month ago on 2.5 mg (Eli Lilly). I'm paying out of pocket, so it's expensive, but I had almost no side effects. The medication worked great for the first 4 days after each injection, then the appetite suppression wore off during the last few days of the week. By week 4, it wasn't suppressing my appetite much anymore, so my doctor and I decided to increase to 5 mg.
I lost 7.4 lb in my first month (starting weight 182 lb) and have now lost 11.4 lb total. My goal is 145 lb, mainly to improve my health and reverse my prediabetes. I'm still in my 30s with young children.
I took my first 5 mg dose last Saturday, and it hit me hard. I slept almost all day Sunday and felt very sick through Tuesday. I had severe abdominal pain that radiated to my back and side, felt extremely full, and couldn't eat or drink for about 24 hours. On Monday evening I managed about 350 calories (mostly cauliflower rice) and about ½ cup of water. I gradually started eating small amounts, and today I'm finally feeling like myself again.
I couldn't get a timely appointment with my doctor, and my next injection is due in two days. Has anyone successfully split the 5 mg KwikPen into 2.5 mg twice a week (for example, every 4 days) to reduce side effects? Or did your body adjust after the first 5 mg dose? I can't go through that again.