u/Jaded_Scallion613

Ovulating naturally with PCOS-IR + Hashimoto’s after Clomid/Letrozole made everything worse — 3 cycles of Mira data + a weird FSH glitch I figured out. Anyone else?

Hey everyone, sharing my journey in case it helps someone.

I have IR-PCOS and Hashimoto’s. My cycles were 45-55 days and mostly anovulatory. My doctor put me on Clomid then Letrozole — Clomid gave no ovulation, Letrozole my biggest follicle was 9mm. Both medications made my cycles significantly worse. I stopped both and focused on the root cause instead.

What actually helped: Metformin XR 1500mg, Inositol 40:1, optimizing my thyroid (TSH needs to be below 2.0 for TTC), and a full supplement protocol targeting insulin resistance. Three cycles later I’m ovulating naturally every single cycle.

What my data shows across 3 cycles:
Cycle 1: Ovulated CD13, LH peak 32, 14 day luteal phase

Cycle 2: Ovulated CD20, LH peak 44.5, PdG maxed Mira’s scale by 8DPO

Cycle 3: Ovulated CD19, LH peak 26.7, E3G peaked at 396 — strongest cycle yet

The stuttering follicle pattern: Every cycle my LH rises partially, drops back down, then surges properly days later. If you see this and have PCOS don’t panic — keep testing twice daily, the real surge will be significantly higher and sustained.

Mira FSH glitch: Mid-luteal FSH on Mira is completely unreliable. Mine hit 80.5 this cycle and 72.7 last cycle — menopausal range, obviously not real. I figured out it’s cross-reactivity with PdG. When PdG reads low, FSH spikes artificially. When PdG is high, FSH reads near zero. They’re on a seesaw. Ignore all mid-luteal FSH readings on Mira entirely.

Still in my TWW for cycle 3. If anyone has a similar experience with PCOS, stuttering follicles, or Mira quirks I’d love to hear — and any advice welcome 🤍

u/Jaded_Scallion613 — 4 days ago