u/LeastBad6994

Pioglitazone found non-inferior to hydroxychloroquine as first line treatment. Pioglitazone prevented progression in 87.5 % of cases. One caveat, in my mind, is that the pioglitazone treated patients with a smaller amount of LPP scalp involvement than the hydroxychloroquine group so I don’t think they can be directly comparable here. However, researchers concluded no significant differences between pioglitazone and hydroxychloroquine in terms of LPPAI reduction and global photographic assessment (GPA).

Here is study link. I do not have full text:

https://onlinelibrary.wiley.com/doi/10.1111/ddg.70362