Feeling lost after loss, endo diagnosis, & failed IUI—where do I go from here? (IVF vs. Laparoscopy?)
Hey everyone, I just really need to vent and hopefully get some insight from people who actually get it.
TTC has been such a heavy, exhausting journey. Back in July 2024, I got pregnant using Letrozole, but unfortunately lost the baby shortly after (we still don't know why). After taking time to heal, I started trying again and switched OBGYNs. Last November (2025), my new doctor discovered I have endometriosis. It hasn't been officially staged, and I haven't had surgery for it yet.
Since the diagnosis, I feel like I've tried everything to tackle this head-on:
Endo suppression: Did a course of Norethindrone + Letrozole.
Weight loss: Completed 2 rounds of GLP-1 medication.
Optimized labs: Brought up and stabilized my Vitamin D3, B12, and Iron levels.
We got back to active TTC two months ago and just had our first IUI fail. It’s devastating.
I’m so frustrated. Watching literally everyone around me get pregnant—and so easily—is getting harder to swallow every day. It feels so unfair.
For those who have been through endo + secondary/unexplained infertility:
Would excision surgery (laparoscopy) make a difference at this point? Did finding/removing endo help you conceive naturally or through IUI?
Should we skip more IUIs and jump straight to IVF?
What else can be done differently? (Protocols, testing, RE consults, etc.?)
I’d love to hear your experiences, advice, or even just some reassurance. Thank you so much for reading. ❤️