r/whatworkedforme

Hey guys we have been TTC for about 9 years. I used to be a skinny woman at the start of my journey but now I've gained a lot of weight mainly due to cortisol and infertility-related depression. I've also been binge eating and unhealthy eating for a while now so thats also an issue. I was reading a couple of subs a while ago in the IVF space and I saw G͏LP mentioned where women were talking about going on GL͏Ps and stopping before treatment for weight loss for better results. So I was wondering if that is the case for IUI too. I am not a scientist or anything who understands medicine but I have read that losing weight can help improve ovarian function. I mentioned this to my doctor and she recomm͏ended a certain br͏and. But I have already taken way too many medicines throughout my journey and I have had really bad experiences with doctors recommending specific expe͏nsive brands. I have taken so many medications that I feel like my body and maybe my liver will not tolerate just anything at this point. I also looked it up on the internet and the reviews were pretty mixed so I am not sure how to go about it. If there is a proper way to research options before spending that kind of money. did some manual research and I also saw some resources mentioned. Listing them here PubMed, StatPearls, ClinicalTrials.gov, Drugs.com, MDPI Pharmaceutics and the ADA Standards of Care but would i be able to understand them, probably not.. So yeah I was wondering how people go about this or if you even recommend going on GLPs before IUI or should I just go ahead with IUI? It is expensive and I cannot really afford IVF so IUI is basically my only option. Sorry if this post is a mess.. I just wrote what came to my mind.

Always wanted to have a family of myself but found out im actually infertile, factory is out of business. I don't want to adopt as that'll never be my kid genetically. What is the point of life if you cant create a family? Just work, live and die of old age? Life just seems meaningless after that information at the reproduction center. Anyone in the same situation? If so whats the reason you want to continue living?

Hi I and my husband both are 33
My amh in jan was 1.09 and in may last week if came 0.75
My husband report is as follows
Sperm concentration- 12million/ml
Motility 36% in which rapid progression is 2 percent
Slow progression is 19 % and non progressive is 15 %
Immotile 64%
Normal forms 2%

We went to a doctor in Bangalore in a famous hospital. She has told us to go for IVF she is an IVF expert. One of the top most doctor here.

Shes saying otherwise we only have 8-10 % of chances.

My other things are normal.

I have also visited another famous hospital where the top doctor also knew the doctor we are going to.

We are scared and not able to understand what to do next.
Please help.

This is our first TTC cycle, so anything that worked for you (monitoring implantation cramping) & info about that would be appreciated!

~6-7 DPO: I started getting a strange, very intense pressure/pulling cramping feeling on my right abdomen. It was from slightly to the right of my belly button, all the way down to my urethra almost, and would get worse when I had to pee. It was more of an uncomfortable twinging than it was painful. It lasted ~4 days.

10 DPO: The cramping feeling vanished (I could still feel a dull throb sometimes in the area, but it was no longer consistent).

11 DPO: Today. AF is supposed to come tomorrow. I have taken easy at home & FRER tests every day since 7 DPO, and they’re still all negative.

Has anyone experienced a cramping like this? I have never experienced this feeling, so it was what I assumed to be implantation. But still just BFNs. Has anyone had these before?

My story is a bit of a unique one and I guess I’m just looking for some hope. I’ve been trying for a second since end of 2023. Up until then conception had been easy for me. End of 2023 was a chemical followed by 2 years unexplained infertility. I had just about all the treatments, and medications. Never once saw a positive test in those 2.5 years

Finally in March I did my first iui and to my complete shock it was successful. Unfortunately we found out a little over 6.5 weeks it was a blighted ovum/loss. The loss process has taken 1.5 months already and I still haven’t even ovulated - the one thing that used to be clockwork for me.

Im just so terrified it’ll be another 2+ years before I get pregnant again. I have no clue what caused my infertility and what caused this random conception. I’ll do another iui maybe next month but I won’t be taking medication this time (there was a twin scare).

Has anyone had a similar story? Where they had unexplained infertility followed by loss and actually went on to get pregnant again?

Has anyone used GLP-1 peptides for infertility and/or prior to pursuing IUI/IVF? I've seen many anecdotes of accidental pregnancies while on these medications. I know they're not recommended if you're actively TTC.

I'm 37, 2 years of TTC with no success. I've never had a positive pregnancy test. I have regular 27 day cycles, 11-12 day luteal phase. I do have insulin resistance and I've been working to improve it over the last year and a half. I've lost 15lbs, lost inches in my waist and gained muscle, and dropped my A1C from 5.7 to 5.3. But I am still overweight. I've been on a lower carb diet but the weight loss has slowed down.
Other stats: AMH dropped from 0.9 to 0.6 in the last 6 months. FSH: 9.22 LH: 4.69 AFC: 29 Prolactin: 23.4 (slightly high). Ovulation tracked and regularly confirmed with BBT. Thyroid normal. No endo symptoms.

I've seen two different REs who've suggested IUI and IVF but due to "unexplained" infertility and age, I want to give myself the best chance before pursuing these difficult and expensive options, or hopefully be able to conceive without them. I'm debating pursuing a couple months of GLP-1 treatment (Tirzepatide) to drop more weight quicker and improve my insulin resistance, and improve my chances. We won't be scheduled for IUI/IVF for at least a few months no matter what.

What I've tried:
- 2 hysteroscopies (no polyps or fibroids)
- an HSG and an SIS (tubes clear, no blockages).
- semen analysis was "very good, above average".
- exercise (weightlifting and cardio training minimum 2 days a week, usually 3)
- acupuncture and traditional Chinese medicine
- keto diet (difficult to sustain, didn't last long)
- lower carb, higher protein, higher fiber diet (currently)
- metformin (currently)
- supplements: Ubiquinol, Myo + D Chiro Inositol, Fish oil, NAC,
- going on vacation + "just relax"

Please give advice to a pretty sad girl,

I’ve just failed my 4th medicated cycle, I moved from clomid, to Letrozole (which I did not respond well too) and then Gonal F injections. This month doing gonal F and trigger shot made me so hopeful, one great follicle and a possible second one 39 progesterone result day 21 of this cycle, every symptom under the sun and boom not pregnant.

I’ve had a HCG done 8 weeks ago, all my bloods are great including my thyroid which is actually fantastic, I’m also only 25.

My partners semen analysis was also incredible.

My fertility specialist said it’s up to me whether I do IUI this cycle and I’m unsure!

I’ve always noticed little CM during ovulation so maybe the iui would help if I do have thicker cm? Did anyone else do one with no partner male factors in the way?

I’m honestly feeling hopeless and exhausted, I know it’s going to be only the 5th medicated cycle month but I just never thought it would take this long, I had so much hope when I met the fertility specialist back in Jan

My known issues before I saw the specialist was the incredibly low progesterone and 8 day luteal phase ALWAYS.

I just feel like giving up, was IUI the final piece of the puzzle for anyone?

It’s been 2.5 years that we’ve been trying to grow our family. I (35F) got all my results back normal, my scans all normal. Hubby (38M) has low count (16millions) but over 50% motility. Doctors said they have seen couples conceive with lower sperm count.
My morale has been affected as I don’t know why this isn’t happening for us. Hubby tried Clomid for 3 months noticed an increase in volume but no baby. Also, I’ve never been pregnant before. Could this be a mental/ psychological blockage ? I do feel scared of giving birth, but I do want to be a mum so badly. I’ve waited to meet the right man, to own a home and to have financial security before deciding to have a family.
I feel stress at work but who doesn’t. Could it be the stress preventing me getting pregnant?
Please tell me what worked for you and any recommendations are appreciated.

I just had my HSG this morning. I would say it’s was mildly to moderately plainly. I didn’t have a horror stories like some others I’ve heard.

My question is, I’m ovulating tonight, and they’ve told me to abstain from sex to avoid infection. The thing is I’m taking anti biotics, and I’m ovulating like now so I don’t want miss a whole month.

Would you try and risk the chance of infection (even though I’m taking antibiotics), or would you just waste the month?