u/tlc_ttc_789

I have an interesting success story I thought people might like to read. I'm 38, DOR (AMH .13) and have endo. I've had 4 unsuccessful IVF rounds. Only 1 that produced 2 day-3 embryos. I was about to start up again this year in April doing a Lupron downregulation protocol with a luteal phase start. That meant waiting until after I ovulated naturally, then doing low-dose Lupron priming (20 units/day for about a week) before I was to start stims.

They didn't order pelvic rest and my husband and I had sex around ovulation. To my surprise, on 10 DPO, I got a positive test! Of course I was a little worried since I had conceived while on Lupron, but I found retrospective studies of people conceiving on Lupron and everything was fine, and my clinic didn't seem concerned. (https://link.springer.com/article/10.1186/s12958-021-00732-1 and https://www.researchgate.net/publication/287191212_Outcome_of_inadvertent_administration_of_a_gonadotropin-releasing_hormone_agonist_in_early_pregnancy )

And everything seems to have turned out fine! I'm 21 weeks and just had a good anatomy scan. We are so thrilled. I think the Lupron helped calm down my endo enough for implantation to occur. I'm not advocating anyone go against their doctor's directions. My real reason of posting is that I would love for some researcher to look into this for women with endo. And I want to encourage women with a super low AMH like me! I was always looking for success stories.

TLDR; got pregnant while doing microdose Lupron priming AFTER I ovulated. 21 weeks and great anatomy scan.

I have an interesting success story I thought people might like to read! I'm 38, DOR (AMH .13) and have endo. I've had 4 unsuccessful IVF rounds. Only 1 that produced 2 day-3 embryos. I was about to start up again this year in April doing a Lupron downregulation protocol with a luteal phase start. That meant waiting until after I ovulated naturally, then doing low-dose Lupron priming (20 units/day for about a week) before I was to start stims.

They didn't order pelvic rest and my husband and I had sex around ovulation. To my surprise, on 10 DPO, I got a positive test! Of course I was a little worried since I had conceived while on Lupron, but I found other instances of people conceiving on Lupron (usually during long Lupron suppression) and everything was fine, and my clinic wasn't concerned. And everything seems to have turned out fine! I'm 21 weeks and just had a good anatomy scan. We are so thrilled. I think the Lupron helped calm down my endo enough for implantation to occur. I would REALLY love for some scientists to research this as a possible treatment for endo and a way to conceive without IVF.

Also, I'm not advocating anyone go against their doctor's directions. My real reason of posting is that I would love for some researcher to look into this for women with endo. Several retrospective studies looking at similar situations do not show adverse outcomes. Here are a couple of them: https://link.springer.com/article/10.1186/s12958-021-00732-1 and https://www.researchgate.net/publication/287191212_Outcome_of_inadvertent_administration_of_a_gonadotropin-releasing_hormone_agonist_in_early_pregnancy

TLDR; got pregnant while doing microdose Lupron priming AFTER I ovulated. 21 weeks and great anatomy scan.

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