u/No-Chemical3765

Has anyone failed Yuflyma? If so, which biosimilar(I don’t have insurance) has worked for you? I’m going on my 6th month and there’s hardly to any change. I’m still in a lot of pain.

I’ve been an athlete my entire life until my last year in high school when I developed AS(didn’t know what it was at the time). Since then(8 years), My body has slowly and my pain has significantly increased. I just started biologics a few months ago. I’m wondering if there’s any hope of me being active again? My dream is to get into strength training, weight lifting and I really want to try Pilates? Are any of you able to be active, if so how long did it take you to get to that point and how’s your pain during and after? As of now I can only manage light waking 20 minutes max. I also have pelvic floor dysfunction so that limits me as well.

For those that take Yuflyma, has it been working for you? If so, how long did it take, how much have you improved and were there any side effects?

I’m seronegative and I’ve been on it for 4 months now and I honestly don’t see that much improvement. My back hurts so incredibly bad and the rest of my body is still inflamed. I have been sleeping on a broken bed as well so idk.

I’ve also been having some weird things going on idk if they’re side effects .I’ve been experiencing vaginal dryness and itching, facial swelling, ear pressure and sinus congestion. I’m thinking I have a sinus infection maybe even a vaginal bacterial infection.

YouTubers living in The Bahamas, where did you send your google Adsense pin? Was it to your p.o.box and if so, did you have any problems receiving it? I’m on my 4th pin in 4 months & haven’t received it in my P.O. Box. They’re saying they haven’t received any of them yet.

For those that are seronegative, how long did biologics take to start showing some improvement?

I’m on my second dose of yuflyma and I haven’t seen a difference as yet. I know it can take up to months but I just want to know when others have started to feel even the tiniest bit of improvement. Any relief would feel amazing to me rn. I just wish I could take it more frequently but I know that’s just me being desperate for relief and not how it works.

Hi(F), I started PT for hypertonic pelvic floor & significant nerve/pelvic pain and SI/back issues. I’ve had severe pelvic nerve pain and pressure that was debilitating before starting Lyrica, which helped a lot, but I still have tightness and flares (especially around my period, which can take 2–3 weeks to settle).
We did about 5 sessions of external work/exercises. Internal work was then introduced unexpectedly, I arrived and the table was set up and I was told to undress. I didn’t feel prepared for it, and I wasn’t told it would be happening ahead of time. I also didn’t start internal work in the first session because I couldn’t tolerate it at that time.

I’m a virgin and have never used tampons, so internal work is very sensitive for me. I was already in pain (~6/10) due to my period just ending and said I wasn’t sure I could tolerate it. She convinced me so I said we could try & if it’s too painful stop. The internal exam itself was very painful, even with minimal insertion. I was bridging and trying to move away from the pain I was feeling.
Within less than 24hours I had a major flare:
intense nerve pain (similar to pre-Lyrica levels)
increased pelvic tightness/pressure urinary discomfort
mostly bed-bound for several days
I’m still recovering from it.
My PT’s response was very clinical and focused on guarding/tension and that flares are part of the “data,” and to continue dilator work. I felt like the severity of the flare and functional impact wasn’t really acknowledged.

I’m now unsure if continuing internal work is appropriate right now. I don’t currently have strategies for flares other than waiting it out, and I can’t function during them. I also have back/SI issues and am starting biologic medication soon for an inflammatory condition that may be contributing.

My questions:
Is this level of flare after early internal work normal?
Is it typical for PTs to expect this level of functional setback?
Should internal work/dilators be paused if it causes multi-day bed-bound flares?
Or is this just part of the process?
Trying to understand if my reaction is expected or if the pace is too aggressive for my current state. This is what I feared about doing the internal exam in the first place. I know I’m getting better but it was so hard physically and emotionally being pushed back to square one. Knowing I’m stuck in bed. Can’t even walk to the kitchen.

I started PT for hypertonic pelvic floor & significant nerve/pelvic pain and SI/back issues. I’ve had severe pelvic nerve pain and pressure that was debilitating before starting Lyrica, which helped a lot, but I still have tightness and flares (especially around my period, which can take 2–3 weeks to settle).
We did about 5 sessions of external work/exercises. Internal work was then introduced unexpectedly, I arrived and the table was set up and I was told to undress. I didn’t feel prepared for it, and I wasn’t told it would be happening ahead of time. I also didn’t start internal work in the first session because I couldn’t tolerate it at that time.

I’m a virgin and have never used tampons, so internal work is very sensitive for me. I was already in pain (~6/10) due to my period just ending and said I wasn’t sure I could tolerate it. She convinced me so I said we could try & if it’s too painful stop. The internal exam itself was very painful, even with minimal insertion. I was bridging and trying to move away from the pain I was feeling.
Within less than 24hours I had a major flare:
intense nerve pain (similar to pre-Lyrica levels)
increased pelvic tightness/pressure urinary discomfort
mostly bed-bound for several days
I’m still recovering from it.
My PT’s response was very clinical, there was no empathy or response to my current pain lie “I’m sorry you’re going through this”, she just focused on guarding/tension and that flares are part of the “data,” and to continue dilator work. I felt like the severity of the flare and functional impact wasn’t really acknowledged.

I’m now unsure if continuing internal work is appropriate right now. I don’t currently have strategies for flares other than waiting it out, and I can’t function during them. I also have back/SI issues and am starting biologic medication soon for an inflammatory condition that may be contributing.

My questions:
Is this level of flare after early internal work normal?
Is it typical for PTs to expect this level of functional setback?
Should internal work/dilators be paused if it causes multi-day bed-bound flares?
Or is this just part of the process?
Trying to understand if my reaction is expected or if the pace is too aggressive for my current state. This is what I feared about doing the internal exam in the first place. I know I’m getting better but it was so hard physically and emotionally being pushed back to square one. Knowing I’m stuck in bed. Can’t even walk to the kitchen.

I’ve been diagnosed with RA for seven years(by a GP). I haven’t been on any proper treatment only NSAIDs. I’m going to a new Rheumatologist tomorrow. So far the only positive bloodwork I’ve had is a mildly elevated CRP. I took ana, esr, anti ccp & hla-b27(I took these while on 20mg of prednisone if that matters). When I got diagnosed in 2019 I had a positive ana & crp. For imaging I’ve gotten X-rays of every joint none show any damage. Ive also gotten mris which show straightening & curvature of my spine as well as a lumbar transitional vertebrae, lumbarlization of S1 & mild effusion of my si joint. I haven’t gotten any results back that really show the extent of inflammation I haven’t used yet going on in my body. Almost every part of my body gets inflamed but some days are better than others and I’m afraid I’ll go to him on a good day and have nothing much to show. I feel really nervous and I just want to know if anyone was able to receive a diagnosis with limited or no positive bloodwork and joints that wasn’t insanely inflamed at the visit. My shoulder has been swollen pretty bad since 2021 so I know that’s proof. But my other joints aren’t as inflamed.

For those with a hypertonic pelvic floor & did physical therapy, how long did it take you to start seeing results and for your pelvic floor to revert to it’s normal state?

During the consultation, within the first 3 minutes, he says he thinks I have Ankylosing Spondylitis. When he examined my shoulder, he was actually appalled by the state it was in and said it was a “bad shoulder” & mentioned the swelling. I am currently tapering off 20mg Prednisone on and 15mg Meloxicam.
Here are my labs:
CRP: 1.0 mg/dL (Lab range is 0.05 - 0.5). It is flagged with an "H" for High, Anti-CCP, RF, and ESR were normal. He was going to start Methotrexate but took it back because I haven't had an ANA test yet. I showed him my Ana was elevated in 2019 but he forgot when prescribing it & thought it was a recent test. He told me I have "no signs of inflammation." That was his reason for taking the prescription back. And he said he doesn’t know what’s going on with me when he’s getting me tested for AS. When I asked me not being inflamed is possible since 1.0 is double the limit while I'm on steroids, he got extremely rude and basically saying he’s going by science."
I wasn't even arguing for those particular meds, I was asking for a clear understanding of his reasoning and how he would treat me if all my test negative seeing how that’s very possible. I was concerned because he kept acting like I dont have inflammation and pains which I clearly do. He treated me like a pill-popper just for wanting to understand my own results. He even told me I should find another doctor because I was asking follow-up questions. He ordered me to get a hla-b27 test, sacarum/coccyx mri & the Ana test done. The problem is where I’m from it takes 2 weeks to get the bloodwork results back.

Is this normal, to not give me anything in the meantime when I’m in a lot pain until the ana comes back? He told me to go to the er to get medication then they’ll send the results back to him.. like what?

Ps. He’s almost 80 if not 80 already

I’m 25 years old, I’ve been untreated for 8 years and I feel like I’m being gaslit by my Rheumatologist. It’s like he flipped a switch. During the consultation, within the first 3 minutes, he says he thinks I have Ankylosing Spondylitis instead of Rheumatoid Arthritis which a GP diagnosed me with. When he examined my shoulder, he was actually appalled by the state it was in and said it was a “bad shoulder”. He said I’d need a shot because it was so bad (though he weirdly didn't order any imaging for it & never gave the shot).

I am currently on 20mg Prednisone which he’s tapering he off of, and 15mg Meloxicam.
Here are my labs (ps. A previous Rheumatologist ran my labs but she thought I was too young for an autoimmune disease so I brought them to this current Rheumatologist):
CRP: 1.0 mg/dL (Lab range is 0.05 - 0.5). It is flagged with an "H" for High.
Other Labs: Anti-CCP, RF, and ESR were normal.

He was going to start Methotrexate but took it back because I haven't had an ANA test yet. I showed him my Ana was elevated in 2019 but he forgot when prescribing it & thought it was a recent test. Now that he’s tapering my Prednisone, I’m in more pain, and I’m starting Physical
Despite the "H" on my labs, my symptoms and the fact that he saw the swelling with his own eyes, he told me I have "no signs of inflammation." That was his reason for taking the prescription back. And he said he doesn’t know what’s going on with me like he has no clue when’s getting me tested for AS. When I asked me not being inflamed is possible since 1.0 is double the limit while I'm on steroids, he got extremely rude. He kept cutting me off, saying "Can I talk?" and "I'm not giving you the meds and basically saying he’s going by science."
I wasn't even arguing for those particular meds, I was asking for a clear understanding of his reasoning and how he would treat me if all my test negative seeing how that’s very possible. I was concerned because he kept acting like I dont have inflammation and pains which I clearly do. He treated me like a pill-popper just for wanting to understand my own results. He even told me I should find another doctor because I was asking follow-up questions.
Here’s some of the pain I deal with: I have systemic pain and inflammation almost everywhere, wrists, ankles, knees, back and shoulders. My neck and back are the worst tho. I have neck straightening and exaggerated lumbar curvature. I also have pelvic floor dysfunction, which makes moving even harder. He ordered me to get a hla-b27 test, sacarum/coccyx mri & the Ana test done. The problem is where I’m from it takes 2 weeks to get the bloodwork results back.

Is it common for doctors to ignore a "High" CRP just because it's not "high enough," even when the patient is on 20mg of Prednisone & 15mg meloxicam which can affect the results? And to withhold prescribing any meds when the patient is in a lot of pain because they don’t have an Ana test?