u/NoFigure3407

Hi everyone,
I’m 32, no kids, and have endometriosis(stage IV) reoccurrence with one laparoscopic surgery done 3y ago. I’m trying to improve my overall health and understand what might help my chances of conceiving.
I’d really appreciate any advice or experiences on what helped you (treatments, lifestyle changes, supplements, fertility steps, etc.). I’m feeling overwhelmed by information online and would love real-life perspectives.
Thanks in advance.

Hi all,
Looking for advice/experiences.
Someone completed CAPOX (oxaliplatin + capecitabine) for stage IIIb colorectal cancer about 5 months ago (5–6 cycles). Since then they’ve had neuropathy in hands/feet, and it seems to be slowly getting worse instead of better. One finger is now very stiff and can’t fully extend. They are on gabapentin but it doesn’t help much.
Is it still considered normal for oxaliplatin neuropathy to persist or even worsen months after finishing treatment? Did anything actually help in your case (time, meds, physio, etc.)?
Also, in your country for stage IIIb colorectal cancer, what is the usual follow-up schedule after treatment to monitor recurrence? How often are CT scans done, and what blood tests are typically checked (CEA etc.)? And how often is colonoscopy usually repeated?
Thanks in advance for sharing your experience.

My mom 67yo recently passed away from metastatic melanoma, and I’m trying to understand whether her care followed a typical standard or whether there were avoidable delays. I’m not looking to blame anyone — I just want honest perspectives from people familiar with melanoma care (patients, caregivers, or medical professionals).

Timeline:
Aug 2023: Stage II melanoma on upper back. Surgery removed tumor + lymph nodes (needed a second surgery for remaining infected nodes).
Jan 2025: Completed 1 year of nivolumab immunotherapy.
April/May 2025: Scan clean no any sign of cancer.
Dec 2025: CT found 4.3 cm adrenal mass.
Jan 2025: was referred to an endocrinologist who took many analysis and excluded a thyroid issue
Feb 2026: Biopsy confirmed metastatic melanoma (Stage IV).
Apr 7, 2026: Right adrenalectomy (about 5 weeks after biopsy due to scheduling delays). Initially recovered well.
Early May: Developed abdominal swelling, cough, and weakness.
May 19: Hospitalized locally, treated for suspected infection (no improvement).
May 26–27: Transferred to oncology hospital; very weak. Paracentesis removed ~2.5L fluid (ascites).
Tests showed hepatitis B reactivation → immunotherapy was delayed pending antivirals + gastroenterology clearance, which caused additional days of waiting.
Imaging later showed multiple abdominal metastases and pleural fluid.
PET-CT results also took several days to return and were not marked urgent.
During this time, her condition rapidly worsened (high inflammation, vomiting, severe weakness).
ICU admission followed after sudden deterioration; she was intubated and passed away a few days later. We were not prepared to lose her so soon, and neither was she. That has been the hardest part.
Until her final day, we hoped she would receive at least one dose of immunotherapy or chemotherapy. We know it may not have changed the outcome, but we wish she had at least been given that chance.

What I’m trying to understand:
Is ~1 month wait for adrenal surgery after biopsy considered normal?
Is delaying immunotherapy due to hepatitis B reactivation standard practice?
Do these timelines sound typical in other countries/centers?
Or does this sound like aggressive disease progression vs possible treatment delays?
I understand no one can know if the outcome would have changed. I’m just trying to get realistic perspective from others who have seen similar cases.

One additional detail: my mom had no other major health problems. Aside from the hepatitis B reactivation with a very high viral load, her routine blood tests—including liver function, kidney function, and other standard laboratory tests—were generally normal. She was feeling well before the adrenal surgery, with good energy and quality of life, which is why her rapid decline over the following two months has been so difficult for us to understand.

Thank you!