Struggling to understand mother’s rapid septic decline
My mother recently died from sepsis/septic shock after a very complicated medical course, and I’m trying to better understand what medically happened and whether there were things I could realistically have done differently as her primary caregiver.
She had FIGO Stage IIIC uterine carcinosarcoma and underwent an open hysterectomy only three months ago. After surgery, she had a UTI that was immediately treated and was resolved. Later, after her second chemo, doctors discovered kidney obstruction/hydronephrosis, which they believed was likely related to the tumor obstruction. Ureteral stents were placed first, her creatine was normalized. But two weeks later , her urine output was super low, so the doctors proceeded with a PCN.
Things declined very quickly after that. Her urine output remained low even after the PCN, creatinine worsened, and she eventually developed severe sepsis/septic shock. She later required dialysis and ventilation, and her blood pressure became extremely unstable despite medications.
I keep replaying everything wondering:
- whether the obstruction should have been caught earlier,
- whether PCN should have been done earlier instead of trying stents first,
- whether poor oral intake/nutrition could have significantly worsened the outcome (she was throwing up everything she was eating at the later stages)
- whether this level of kidney failure can genuinely develop within days in advanced cancer/sepsis,
- and whether this sounds medically like a situation that was already extremely high risk despite treatment.
I fully understand nobody here can judge a complex case perfectly without records, but I’m trying to understand the likely medical sequence and whether there were realistic missed opportunities versus an overwhelming disease process.
I was her primary caregiver through all of this, and I think my brain is struggling to separate grief from responsibility.