CEO is adamant that our homopolymer pegylated lipids are block polymers. IUPAC Goldbook is a bit nebulous on the definition but does define block polymers as macromolecule blocks (plural).
I know applicant is entitled to terminology contrary to the commonly accepted meaning, but the MPEP does state that the term must be redefined in the specification in such instances.
If claim language says "a block polymer of the formula X" wherein formula X is clearly a homopolymer and "block polymer" is not defined in the specification, would this create a 112(a) issue?
Is it possible to file a provisional in the US, follow up with a non provisional within a year, and then within another year file a PCT claiming priority to both?
Im not familiar with EPO law and how they apply their equivalent of 102(a)(2).
Received a preliminary pass on my exam taken today. In both my morning and afternoon session I encountered no mailing or facsimile questions.
I did encounter two questions about EFS. One about the date or receipt for a transmittal sent from California at 10 PM and another about rules regarding EFS submission for applications under a secrecy order
Im trying to calculate structures for surfactant micelles in the 10 nm range. I have conformation search/DFT optimized structures for the individual surfactant molecules.
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My goal is to determine the distance between the polar heads of each surfactant molecule. Any ideas? I have an aging lenovo gaming computer lol. Any web based platforms similar to Rowan Sci?
Currently drafting a budget and soliciting letters of support/intent. I'm trying to entice consultants by having them include an hourly rate in writing.
Past awardees, what have you paid yourself, core members, and consultants?
I see a lot of commercially available succinate linked sterols and biomolecules on Reaxys, but no references on how to prepare them.
Do any of you conjugate chemists have a preferred prep/reference to prepare such compounds? Both the diester and the mixed amide/ester from the amino PEG?
Has anyone who incorporated in California found any microgrants or pre-phase 0 funding opportunities that can be used for grant writing assistance, such as EVG?
Has anyone incorporated elsewhere and used state resources to help fund an SBIR application for an entity in California?
Really enjoyed Mukherjee's book and I'm working through Arney's work as well.
What are some of your favorite pop science reads in oncology?
Im a chemist with no former oncology exposure working for a small pharma company. Considering listening to DeVita's next.
I want to know if TKI-resistance non-small lung cancer has ever been sequences and is available in the cBioPortal (or other platforms) database. I also want to search through the most common notations for a particular list of genes that are associated with homeostasis of a specific lipid.
I'm pretty new to bioinformatics. Is this something that some one can actually do?
Decided to finally buy the PLI course after studying using a 3-ring binder from 2022. Got a 60% on the exam in 2024.
Did everything they told me to over 6 months and I still score almost exactly the average on all three practice tests. Did anyone who did similarly just YOLO it and schedule their exam? Why are the exam averages so low (~60%) if they advise getting an 80% before scheduling your actual test date?
Didn't make the cut this cycle for the NCI STEP and feeling a little disheartened. The 10 teams that got selected will have a big leg up for the September cycle.
I attended an NIH SBIR info meeting and was told theyre expecting double the amount of applications come September due to the shutdown.
Has anyone participated in the program before and can share their experiences?
Im part of an NCI training program (STEP) and trying to better understand the healthcare ecosystem. Are there nurses that specialize in oncology? What about lung cancer specifically?
What input do these nurses have on therapy decisions, either directly or indirectly (maybe not on committee but provide observations)
Are there any professional oncology nursing organizations that are public facing that I could get in touch with? Thanks!
I'm looking for textbooks on cancer or pharmacology that focus on mechanism of action, efficacy signals, and biomarker identification
Can a member of the public leave a box of donuts and a flyer in the break room of a cancer center or oncology wing? Would an oncologist even see it?
I have nothing to sell but I am soliciting interviews as part of the NCI STEP training program to apply for federal grant funding
For any SBIR applicants who took an I-CORP program for a new therapuetic, what strategies did you use to contact customers?
I'm focused on oncologists, VCs, and researchers. I haven't had much luck making cold calls or through LinkedIn.