u/Ok_Wind_8318

Looking for similar stories NSCLC IIIB

Dear all,

I would be very grateful if you could share your experiences.

My dad (72) has stage IIIB NSCLC (T4N2M0). When he was first diagnosed in February, his tumor was 6.2×7.2 cm.

After chemotherapy and immunotherapy, he had a partial response, and the tumor has now shrunk to 4×2cm. His doctors now believe he may be a candidate for surgery, which we honestly didn’t expect at the beginning. His lung function is very limited, and removing the entire right lung is not an option. The surgeons will decide during the operation whether they can remove only one lobe or whether two of the three lung lobes will need to be removed (the tumor is in his right lung).

They say the chances of a successful resection is 80%, with a 20% chance that once they open him up, they may find that a radical surgery isn’t possible and then they will have to move to a non-surgical treatment plan instead.

Does anyone here have any similar experience? Were you able to have surgery after chemo/immunotherapy for stage III NSCLC?

I guess the response my dad had is a good one, right? His lymph nodes are still the same though, no changes there. We were told the nodes’ condition is what’s crucial for the surgery.

We have a consultation with the multidisciplinary team scheduled for July 9 to discuss next treatment steps.

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u/Ok_Wind_8318 — 2 days ago

My dad (72) was diagnosed at the end of February, he’s had his second round of chemo+immunotherapy yesterday.

He was suggested Neoadjuvant therapy route with the possibility of surgery, as he is T4N2M0 currently.

He’s on Pembrolizumab 200 mg on Day 1 + Paclitaxel 200 mg/m² on Day 1 + Carboplatin AUC 6 on Day 1; with 21 days in between.

He’s lost 7 kilos in the last 6 weeks. He eats though, his appetite is not completely gone.

Could you please share your experience. What do we have to pay attention too? I’m very worried and he is scared.

Is PDL 1 being 75% a good sign?

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u/Ok_Wind_8318 — 2 months ago