5HTP and Buspirone?
1 no. I have confirmed pelvic floor dyssynergia and rectal hypersensitivity and am making progress in PT with biofeedback (balloon training)
2 just constipation
3 no
4 no
5 Maybe? I tapered off 20mg Lexapro as quickly as safely possible (under supervision) about 15 months ago. I had been taking it for 9 years and 8 at that dose. I also had a catastrophic l4 disc herniation in June 2025 that resulted in needing an emergency microdiscectomy to prevent cadua equina syndrome. It healed well but the constipation started about 8-10 weeks post-op. I was only on opioids for a week.
6 no
Is anybody taking Buspirone and a 5HTP pro-kinetic. I really want to try the Pure Encapsulations MotilPro before I make the jump to Motegrity but am afraid of potential serotonin syndrome. Neither my psychiatric nor GI provider can predict whether or not this will happen, although both say it “should” be okay.
I am currently laxative dependent after taking 2-3 bisacodyl tablets for the past 4-ish months. Magnesium oxide is somewhat effective. MiraLAX is useless. I am trying to determine whether my current motility issues are a result of laxative dependence or organically slow motility.