PCOS but no insulin resistance on paper. Would you still choose Mounjaro?
26F with PCOS here, and I’m stuck deciding whether to start Mounjaro or not.
I’ve seen two endocrinologists, and both basically told me it’s my decision. They said if I feel I’ve genuinely tried everything, medication is reasonable. If I still want to keep trying naturally, that’s also fine.
My labs are confusing because metabolically they look decent:
HbA1c: 5.0%
Fasting glucose: 80 mg/dL
Fasting insulin: 14.04 µU/mL
HOMA-IR: 1.75
DHEAS: 149.9 µg/dL
TSH: 2.5 (T3/T4 normal)
Other findings:
Hemoglobin: 10.6 g/dL
MCV: 59.1
Serum iron: 40
Transferrin saturation: 12.1% (currently treating iron deficiency anemia)
CRP: 13.6
ESR: 45 (being investigated)
Vitamin D, B12, liver and kidney function are all normal.
My biggest issue is weight. I’ve struggled for years, lost weight before, regained it, and I’m honestly mentally exhausted. At the same time, I’m hesitant to start a medication that may need to be continued long term.
I’m especially looking for people with PCOS but normal insulin/HOMA-IR.
Did you still start Mounjaro or Ozempic?
Was it worth it?
Any regrets?
If you stopped, did you regain the weight?
If you decided against medication, why?
I’d really appreciate hearing experiences from people who were in a similar situation.