r/GLP1India

Has anyone switched from Mounjaro to the new generics?

Hi everyone,
I’ve been on Mounjaro for the past 8 months and gradually titrated up to 12.5 mg. I’ve been fortunate to reach a healthy BMI and I am no longer in the obese range.

The only problem is the cost. Mounjaro has become difficult to afford long-term, so I’m considering switching to one of the Indian semaglutide generics that have recently launched.

I’d love to hear from anyone who has made this transition. My doubts are as follows:

  1. Which semaglutide brand did you switch to?
  2. How smooth was the transition from tirzepatide to semaglutide?
  3. What’s your monthly cost now?
  4. Did you notice any difference in appetite suppression or weight loss?
  5. Most important- Have you continued losing weight, maintained your weight, or regained some after switching?

Real-world experiences would be really helpful before I discuss this with my doctor.
Thanks in advance!

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u/StonedArtemis — 16 hours ago

Ozempic Face

So no one outside of my immediate family knows I’m taking GLP-1, I’m not ashamed of it, but it’s still sort of a taboo where I come from.

I was talking to someone the other day about it and they said “Yeah look at XYZ, they’ve got the ozempic face” so I asked them what it meant and they said it’s the face people get when they lose weight using ozempic.

I tried to counter it, saying it’s natural and pretty normal for people’s facial structure to change after they loose a bunch of weight and the person said “no, you can tell when someone has lost weight with ozempic”

So my question is, is ozempic face a thing? And am I going to end up with an ozempic face? And if yes, how do i avoid it?

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u/Maleficent-Month-498 — 17 hours ago

Anyone lose appetite suppression over time?

I’ve been on Mounjaro for about 5 months.
Started at 86.8 kg, now 77 kg (~10 kg down)
2.5 mg × 1 month
5 mg × 3 months (great suppression for the first 2 months, then completely plateaued in month 3)
Currently on my 3rd week of 7.5 mg
The weird thing is that I had much better appetite suppression on 2.5 mg and 5 mg than I do now on 7.5 mg. My hunger and cravings are almost back to pre-Mounjaro levels, even though I’m eating 80–90 g of protein daily and strength training regularly.

Has anyone experienced this? Does the body eventually get used to the appetite suppression, or did moving up to a higher dose help you again?

Also, I always injected in my stomach, but recently I’ve started alternating between my stomach and thighs because I thought the injection site might make a difference.

Has anyone genuinely noticed a difference in appetite suppression depending on where you inject?

Looking for similar experiences and what changes you made helped the weight loss eventually better ? 🙏

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u/nm_3595 — 15 hours ago

Took first shot of 5 mg MJ. No difference!?

Hello

I took my first shot of 5 mg Mounjaro Wednesday evening, it's been 3 days according to glapp it's peak effect but I feel no literally no difference from 2.5.

Nothing in food noise, hunger, side effect nothing.

My weight has slightly gone up.

I took 5 doses of 2.5(golden shot). I am really confused. Bought the medicine from the same clinic same as 2.5.

Has anyone else also observed this. What happens!? Is this okay?

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u/MikeyTJGus — 1 day ago

Acidity and throwing up feeling

Hello, I have taken 3 dozes of MJ 2.5 so far. First dose was a breeze, no noticeable side effects, food noise was gone. Second dose gave a terribly upset stomach after 3 days of the shot - managed it with medicines.

However, dose 2 and 3 have left me with a constant feeling that I am full to the throat and want to throw up. On top of that, I wake up with a acidity type feeling. My doctor has prescribed a nausea medicine on an SOS basis, so I am not sure if it should be taken to manage daily symptoms (will also check with them during my next followup).

Need help on how to manage these better.

Thanks in advance!

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u/OutsideMacaron5660 — 2 days ago

Starting my GLP journey next week 🤞🏽

Done with multiple appointments with the endocrinologist. Checked off all possible risks from other doctors. Now doc has advised to start with either Mounjaro/Yurpeak. Postponing it by a week because of family function.

Any tips/suggestions as I start my journey? Things to do, precautions to take? Choose Mounjaro or Yurpeak? Dosage will be 2.5mg for the first month and then review again.

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u/DopeShope09 — 2 days ago

Zero effect on generic semaglutide 0.25mg after 2 weeks and my doctor says Ozempic is better than generics. Is that true?

FYI- I have used Ozempic 0.25mg earlier this year and lost about 5-6kg on it in a month only, noticed real appetite suppression and some reflux. Stopped for personal reasons. Started an Indian generic (Semasize) mid-June, still on the same 0.25mg starter dose.

It’s been 2 weeks and there is zero effect. No appetite suppression(I’m not sure I can eat whatever and how much I want now but with ozempic I used to get full in few bites ) no reflux, can eat as much as I want with no reaction completely different from how Ozempic felt at the same dose. Lost 0kg so far.

Shipping concern: Ordered online. Arrived with ice packs that had fully melted to water by delivery.

My doctor told me Ozempic is simply a better drug than generic semaglutide. Is this right? But there are so many people going with generics what are you experiences?

Questions:

Did anyone else get zero response on a generic at 0.25mg despite having a clear response to Ozempic at the same dose before?

Has anyone had a heat-exposed shipment (melted ice packs) turn out to be a dud? How did you find out / what did you do?

Anyone using Semasize or other Indian generics post-patent-expiry — good/bad experiences with a specific brand?

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u/Every-Ebb-656 — 4 days ago

Mounjaro's effect on periods

Hi I just started Mounjaro on the lowest dose and am on my second week. The first week went great. Steadily lost about .5kg every day. I suspect a lot of that is water weight.

But this came to a stall on the second week. Weight refused to budge, started to feel the cravings creep back in and then periods started about a week earlier than expected.

I generally have medium to heavy flow but this time there's hardly anything. Did anyone else also feel a major shift like this or is this something concerning I should talk to my doctor with?

Anyone faced something similar here?

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u/genieshin — 3 days ago

I can cross my legs, knee on knee!

I can cross my legs, one knee on top of the other, in public without looking like a perpendicular angle lol. Just a nice acute angle now, also very comfortable! I did it in a hospital waiting room and I just lost my shit because that has not happened in the last 10 years haha! Probably looked very funny when the realisation hit me but I don’t care, I love it!

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u/InstantCoffeeSnob — 4 days ago

Wegovy 2.4mg too expensive now (14k) what generics are people using?

Hi all,
I’ve been on semaglutide for a few months now and it’s worked well, but Wegovy at the 2.4mg dose is running me about 14k, which isn’t sustainable long term. I know there are generic semaglutide options available in India now.
For those who’ve switched, what brands are you using and how has your experience been (cost, availability, any difference in side effects or efficacy)? Also curious if anyone has a reliable pharmacy or source for these.
Appreciate any pointers, thanks!

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u/One-Bridge3056 — 5 days ago

Thanks for the help, Just wanted to post my mrmed experience in NCR/Gurgaon

Thanks to all for helping me, the packaging was awesome and the temperature was all maintained when shipped and sealed, this was delivered to me in 8 hours, they also included a 5 pack needle pack and these 4 alcohol swabs, these all were packed and taped in bubble wrap along with the invoice.

I just removed the shipping label via Gemini to hide my details, Hope this helps you all.

u/anotherNeinYearOld — 5 days ago

Is it expected that the medicine is in effective in week 2 and week 3

Hello All,

I had my first dose of Mounjaro and effects were really good, but week 2i didnt have any effects, and i am kinda worried that it might not work in week 3 as well, is this something you all have also experienced and common for a 2.5 MG dose?

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u/anotherNeinYearOld — 5 days ago

Anyone here had little to no response on semaglutide but succeeded after switching to tirzepatide?

I've been wondering how common this is.

I've been on semaglutide for a while and I'm currently at 1 mg. This is the first dose where I've noticed any appetite suppression at all, but it's been quite mild. Even then, the effect seems to taper off almost completely by day 5 after the injection, and by then it feels like I'm back to baseline. I'm curious if anyone else had a similar experience.

  • Did you go through the full semaglutide dose escalation (or even reach the maximum dose) before deciding it wasn't working?
  • Did you have little to no appetite suppression, fullness, reduced food noise, or meaningful weight loss on semaglutide?
  • What made you decide it was time to switch to tirzepatide?
  • Once you switched, did tirzepatide actually work better for you?
  • How long did it take before you noticed a difference?
  • Was the improvement obvious compared to semaglutide?

I'm especially interested in hearing from people who were genuine non-responders to semaglutide rather than those who switched because of side effects or supply issues.

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u/tripledigitonly — 6 days ago

Hyderabad - Anyone who gives 20% off? (Tirz)

Looking for dealers or stores in Hyderabad who are providing 20% off on MJ/Yurpeak, I'm looking for 15mg if that matters. Please drop references if you've found anyone.

Thanks!

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u/kp_4144 — 5 days ago

Where are you all buying shots from, and how do you verify it’s genuine?

With all the recent news about counterfeit GLP-1 medications, I’m becoming extra cautious.
For those using Yurpeak in Delhi NCR:

Do you buy it online (Apollo, Tata 1mg, PharmEasy, etc.) or from a local pharmacy?

If you buy offline, which pharmacy do you trust?
How do you verify that the pen is authentic?

Has anyone ever had doubts about the authenticity of a pen or had it verified by the manufacturer?

Would really appreciate hearing about your experience .

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u/That-Ad-8843 — 5 days ago

Help! Week 2 on 5 MG. Acid Reflux and bad stomach is killing me 😭😭😭

Started on Monday night and still continuing. I was unable to lose weight earlier but now I can barely eat anything. Only bananas feel eatable, everything else gives me acid reflux. I was dehydrated badly after bad stomach and continued nimbu pani with sugar and salt. Talking Sompraz 40. Eno. Nothing seems to help. I am getting scared if is the only way I can lose weight. Is this the new normal for me.? How can I avoid this?

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u/ADTSR — 5 days ago
▲ 4 r/GLP1India+1 crossposts

Starting Rybelsus today.

3mg for 30 days and 7 for 60 more.

175cm/ 92Kg 35M HbA1c 6.1% - Target weight 72Kg

appreciate your tips and guidance please, and what to expect

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u/WifiTheifNextDoor — 5 days ago

Tried Cheese Maggi on Tirz?

I am looking forward to my cheat meal after a month. For one month, I have only had healthy home cooked food. Just wanted to check if anyone tried maggi on Tirz and if it didn't turn out well!

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u/TraditionalAd5758 — 5 days ago

Weight gain in 1st week of GLP1

So before starting my medication of Generic GLP 1 0.25 dose i lost 2 kgs on my own and went from 116 to 114 and after taking my medication at the end of 1st week i checked my weight and i had gained all of it back . I don’t know what to do
I’m in calorie deficit and do 8k steps everyday so i dont know whats going wrong .

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u/FactorNo31 — 6 days ago