u/Pretty-Chill

Kaempferia parviflora Rhizome Extract Improves Skeletal Muscle Glucose Homeostasis by Upregulating the GLUT4 Signaling Pathway In Vitro and In Vivo

Just stumbled upon this new study that was published only a week ago, on Black Ginger. Quite interesting to see even further evidence on how powerful of a glucose modulating botanical this is! Also cool to see that it seems to increase GLP-1:

>The elevation of GLP-1 by KPE suggests a synergistic enhancement of the SIRT1/AMPK axis, potentially positioning KPE as a natural modulator of GLP-1-mediated metabolic pathways

There was also recently a discussion on here about compounds/botanicals that could potentially inhibit starch metabolising enzymes in our gut. Well, turns out Black Ginger is a seemingly potent inhibitor of these enzymes, even getting close to rivalling Acarbose:

>As shown in Figure 1A, KPE treatment significantly suppressed α-amylase activity in a dose-dependent manner. KPE at 100 μg/mL exhibited the highest inhibitory effect among the tested concentrations. Statistically, the inhibitory activity of KPE 100 μg/mL was comparable to that of the positive control, acarbose, with no significant difference observed between the two.

Certainly keeping in mind here that this is clearly a high concentration of Black Ginger that likely wouldn't be reached with normal doses. However, even at normal doses, it could very well have a significant effect on these starch metabolizing enzymes.

Definitely adding these new findings to the ever-growing list of why Black Ginger is one of my favorite botanicals! Quite the swiss army knife!

Recently someone on here was asking if we'd ever come out with a Mushroom Magic Cacao Baller, which sparked the idea of trying out a dose of 'Ceremonial Cacao' with the Mushroom Magic Advanced powder. I tried it out the other day, using 25 grams of a Guatemalan 'Ceremonial Cacao' and a serving of Mushroom Magic Advanced. It was a very pleasant effect! I already really like the effects of this cacao (in fact this was my last dose of this bag!) but the Mushroom Magic Advanced took it to the next level. There is definitely some unique synergy here, kind of similar to the synergy with the Mushroom Magic Matcha Baller. It kicks up the stimulation of the cacao quite a bit, and adds an additional layer of focus and mood boosting effects to the mix. In fact, it felt quite microdose-esque which kind of surprised me. Would probably go nice with a dose of cognance, which also happens to stack really well with Mushroom Magic Matcha Baller. I'll have to play around with this combination a little bit more, but based on my initial impression, this is a solid stack!