u/SharpSeries6877

Does ovidrel make you feel sad

Does anyone else feel like this after taking ovidrel. I am so sad. Every time I trigger, a few days later I start crying every day until my cycle ends. I feel like I am going crazy.

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u/SharpSeries6877 — 1 day ago

IUI in the morning

I am so nervous. My 2nd IUI is in less than 8 hours and I cannot sleep. I had my baseline ultrasound on Monday and I had one nice 20mm follicle an and a 9.3 lining. I asked my nurse in person what the ideal range is for estradiol since we were waiting to pull the trigger on the bloodwork before receiving instructions to trigger with ovidrel. She said the ideal range is over 100, and they typically trigger anything over 70 so I was feeling hopeful. She said that if it was <70 then she might be concerned that the follicle is actually a function cyst not containing an egg.

Well my estradiol came back at 60.1. I was waiting for instructions in my portal assuming it was going to be cancelled. I then received a message saying I was good to trigger that night. I replied asking if my low estradiol was concerning for a functional cyst, and she replied saying that with PCOS that the number isn’t really reliable and we were good to move forward anyways.

I’m also confused because on CD5, my uterine lining was thicker than it was than on the day of my previous IUI. Wouldn’t the lining be thinner on day 5 versus day 13 of the previous cycle?

I have taken letrozole 6 times with a trigger for timed intercourse at a different clinic and often developed a cyst the following cycle and had to hop on a month of birth control to get the cyst it dissipate before trying another round the next cycle. I did four three unmonitored with clomid. This means that six rounds of timed intercourse took 11 months to go through.

I am just so nervous I can’t sleep right now and we have no insurance coverage, our FSA was cleared by the end of March so this is out of pocket and it feels awful to throw $3k down the drain knowing this might just be a cyst.

It feels sickening throwing money at this knowing I continue to have low estradiol/cysts/low progesterone (always have to supplement). It feels like my body is failing and I’m not going to be able to do a third IUI in June or July this month because I also suddenly need to tend to my parent who lives across the US from me. It’s been the exact same protocol for letrozole->trigger->progesterone and without changing anything it just feels like I’m trying to shove a square brick through a round hole.

Just feel like I am drowning. We have been trying for 4 years and have had to take so many breaks for my mental health, getting re-vaccinated, cysts, poor scheduling, poor communication from my clinic, recover from a laparoscopy, I even lost 90 pounds to try to get things working better and instead I am met with failure and debilitating periods and my mental health is in the gutter.

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u/SharpSeries6877 — 2 days ago

Heyyyy! I had my first IUI on the morning of 4/20 (letrozole 5mg 5-9, Ovidrel trigger 4/18) and MAN am I stressed 9dpiui!!

This was my first IUI but I’ve been seeing a fertility specialist since Jan 23. I have PCOS and endometriosis and after sinking a lot of money in timed intercourse, my RE felt like my chances wouldn’t increase much either an IUI and was pushing me to do IVF.. previously did 3 unmonitored clomid cycles, and 6 letrozole + trigger + timed intercourse. Multiple cycles not able to happen back to back due to developing cysts.

So I got a second opinion and switched clinics out of state about two hours away. So many things are different:

Tubes are open

Stage 2 endo, suspected adeno

Took letrozole on days 5-9 (in the past I have always taken clomid or letrozole on days 3-7)

Had to get re-vaccinated for chicken pox (I don’t hold onto titers, this was my third vaccine)

Had to take a pack of BC to not “accidentally get pregnant after a live vaccine”

AFC was over 60…

Endo thickness 7.89 (I have no idea if this is good or not)

Estradiol 116.8pg/ml

Triggered with one 20mm dominant follicle

Came back 36 hours later with my first IUI. We had to get up at the crack of dawn to drive 2 hours for the appointment. Husbands SA is… beyond perfect. Like, 51 million post wash.

I cried the entire time I was in the clinic. These medications make me awfully emotional.

Procedure was quick, but my uterus felt like a rock immediately after.

Cramping for 3 days. The third day I was cramping so bad I had momentarily convinced myself that I had coincidentally also developed appendicitis. But it went completely away 4dpIUI.

5dpIUI went back for a progesterone check, 14.7ng/mL…. Juuuuust under the ideal threshold so now I am having to supplement with progesterone. My old clinic had me start progesterone right away no matter what, so it was interesting that this clinic waited a few days and did some bloodwork. Too bad I had to take it anyways.

I have almost no symptoms of any kind…. So I’m nervous. Surely I should have SOMETHING going on by now.

Not testing at home until bloodwork next Monday.

Love, a very nervous first time IUI lady.

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u/SharpSeries6877 — 22 days ago