u/Slowgo67

Hi, something I have always wondered: if you lose water weight at first (from any calorie deficit, not just GLP-1 use), wouldn’t it come back after a time? I.e., if you’ve maintained a weight loss for months, why assume that some of it is still “water weight,” assuming you are not avoiding salt?

I know that it’s conventional wisdom that we lose water weight at the beginning of a diet, but why would that stay away, assuming that you’re eating a mix of foods and not just, say, veggies and water-filled fruits, or outright fasting?

Genuine question—please be kind and try not to respond as if I am a moron, even if the answer is obvious to you. Thanks.

Hi, I would love some input. I started on 1.25 2.5 months ago and lost 10lbs in the first five-six weeks (I’m aware not all of that was fat, though for sure a lot of it was, based on my clothes.)

Since then I’ve lost maybe 1.5 lbs and have been much hungrier with a bit of food noise coming back, especially at night.

I only want to lose another 5 or so lbs (I am 5’ 8” and was 162–top end of “normal” BMI). Now I’m 149. The main reason I did this is to try and eliminate my sleep apnea, per my doctor’s suggestion, though my joints feel a million times better. And I used to binge eat—it is a joy not to do the whole shame cycle.

ANYway, I am wondering if the hunger and food noise and much slower loss is my body’s way of saying I should just stay where I am, or whether it makes sense to go up, maybe to 1.5 or 1.6.

“Goal” weights are subjective, to an extent. Any thoughts on how to figure out if the medicine just isn’t working as it used to or if my body is trying to tell me I’m good where I am and it doesn’t want me any lower?

Thank you.

Hi,

I’m confused by all the mini coolers and temperature info for tirzepatide and I wanted some feedback as to whether my thinking makes sense.

I am going on a boat trip in a week and will have refrigeration only sometimes. This means freezing ice packs for travel cases will be unpredictable. I only need to take one dose of tirzepatide during this time.

I have a vial that has only one dose left (I take 1.25, so it is the 8th dose of a vial meant to have 4 weeks worth of a starter dose.) It has been refrigerated for the last 7 weeks.

My question is, if I bring that single dose on the trip, is it ok that it is merely “cool,” not cold? I know that a vial is safe at room temp 21 days after opening. But this vial is obviously older than that (past BUD). It has never not been cold.

Or do I need to find a way to keep it at the proper temp? I will have access to ice (which can cool ice packs but not freeze them properly).

Thank you in advance for any insight.