I finally understand why people never want to come off TRT once they get their dosage right

It took a few months of adjusting the amount and dealing with some minor acne, but now that I have my dosage figured out, the changes are very clear. I originally started this just expecting to put on some muscle and recover faster from my workouts. The physical changes are definitely great, but the mental improvements are the actual reason I want to stay on this forever.

Before I started, I was constantly tired by the middle of the day and struggling to stay focused on my computer work. Now my energy is completely stable from the morning until I go to sleep. I can sit at my desk, finish all my work without needing extra caffeine, and still have the motivation to go lift afterward. My mood is just better overall and the random stress I used to get is pretty much gone.

Just feeling like a normal, energetic person all day is the best part of this whole process. I genuinely cannot imagine going back to how tired I felt before. Have you guys noticed the mental benefits outweighing the physical ones once you found your correct dosage?

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u/Smart_Onion1594 — 12 days ago

Is anyone else secretly terrified of what long term glp1 use will do to us?

I have been on tirzepatide for over a year now and the weight loss is great. I finally reached my goal and my bloodwork looks fine right now. But sometimes I just think about the fact that we do not actually know what taking this stuff for twenty or thirty years looks like. Everyone online treats these drugs like they have zero downsides.

I plan on taking a maintenance dose forever so I do not gain the weight back, but it makes me paranoid. I keep wondering if there is going to be some huge health issue that suddenly pops up a decade from now for all of us. Are any of you guys dealing with this same fear or do you just ignore it and hope for the best?

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u/Smart_Onion1594 — 16 days ago

Has anyone seen the posts claiming glp-1s completely blunt your ability to fall in love?

There is a viral rumor going around social media right now claiming that GLP-1 medications ruin your ability to fall in love. The main argument is that since these drugs suppress cravings and addictive behaviors like drinking or gambling, they also blunt the exact same dopamine circuits in the brain that handle romantic attachment. The claim is that the medication suppresses the feeling of wanting another person entirely.

The theory also suggests that while your oxytocin levels might be perfectly normal, the medication dampens the downstream effects, meaning the actual feeling of falling in love gets blocked. I want to have a serious discussion about this instead of just brushing it off as nonsense. This idea is getting a lot of traction online right now and it will likely scare people away from starting medications that could actually help them. What is a logical way to push back on these specific claims?

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u/Smart_Onion1594 — 20 days ago

Anyone else completely alienate their friend group because they refuse to drink or eat out on cycle?

I am about eight weeks into my current cycle and my social life is basically dead right now. I am tracking every single gram of food I eat, and I absolutely refuse to touch alcohol while my liver is already working this hard to process oral compounds. At first, my friends would invite me out to bars or restaurants on the weekends, but I would always make an excuse or just flat out tell them I cannot eat the food there and am not drinking. After doing that for a month straight, they just stopped asking. I spent my entire weekend sitting in my apartment eating plain rice and ground beef while watching their stories on social media. The physical results in the gym are great, but I feel completely isolated. It is getting to the point where I am wondering if the muscle growth is actually worth losing my entire friend group over. Does anyone else get this strict on cycle, or do you guys just take the hit to your diet and go out anyway?

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u/Smart_Onion1594 — 1 month ago

Why do some people get constipation and others get diarrhea on glp1s?

How do you actually know if you are going to get diarrhea or constipation when you start taking a GLP-1? What decides which set of side effects you end up dealing with? Is it genetics, what you eat, or just your starting gut health?

I am currently taking 7.5mg of tirzepatide and I get severe constipation. I basically have to rely on Mag07 right now. But my friend is on the exact same dose and has the complete opposite problem, so she relies heavily on Imodium. We eat very similar foods, started at the same weight, take the same dose, and even take our shots at the exact same time. Despite all of that, our stomachs are reacting in totally different ways. Does anyone know why this happens?

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u/Smart_Onion1594 — 2 months ago