So exhausted. I don't understand why it isn't happening for us

I don’t even know what I’m looking for with this post. Maybe I just need to vent to people who understand.

My husband and I have been trying for 10 cycles about to go into cycle 11, and I’m reaching the point where I genuinely don’t understand why it isn’t happening. I had a chemical in cycle 1, and I've done 7 letrozole cycles though only 2 with monitoring. In my first monitored cycle we realized that my follicles on meds were growing too big before ovulating so this cycle we added the trigger shot.

I’m 28 with PCOS, but I ovulate on my own. My tubes are open, I had a submucosal fibroid removed, my husband’s semen analysis is normal, and I’m now seeing a reproductive endocrinologist. He reviewed everything and called us “unexplained.”

If someone told me, “Here’s the problem, and here’s how we’ll fix it,” I think I’d cope better. Instead, I’m left wondering every month whether it was the egg, the embryo, implantation, timing, or just bad luck.

I’ve had one biochemical pregnancy, which almost makes it harder. It proved that fertilization and implantation can happen, but then nothing since.

This cycle felt so promising. I had two mature follicles, a beautiful trilaminar lining, a trigger shot, perfect timing, and I’m even on Endometrin. I let myself believe maybe this would finally be it.

Now I’m sitting here at 11 DPO with multiple negative tests, trying to prepare myself for another cycle ending.

The emotional roller coaster is honestly the worst part. Every twinge makes you wonder. Every cramp makes you hope. Every negative test feels like you’re grieving something that almost existed.

What really gets me is that most couples seem to get pregnant within six months. I know statistics don’t predict what will happen to one individual, but it’s hard not to feel like we’ve somehow fallen onto the wrong side of them.

I’m also struggling with the fear of what’s next. My RE wants to do two monitored letrozole cycles and then move to IUI if needed, and I keep wondering if IVF is ultimately where we’re headed.

Did anyone else have completely unexplained infertility and eventually conceive without IVF? Or did you eventually get an answer after months of wondering “why”?
I think I just need to hear from people who have been where I am, because tonight this feels incredibly lonely. I personally don't know anyone who has been through this and everyone tells me when I relax it will happen but I don't believe it.

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u/Still-Passenger9941 — 3 days ago

Switching from Letrozole to clomid after 7 letrozole cycles

Hi everyone,
I just got my period after what was my 7th Letrozole cycle (9 cycles TTC overall) and my doctor wants to switch me to Clomid (50 mg) for my next cycle. For letrozole they started me at 5 mg and eventually I went up to 7.5 and then 10 for my most recent cycle.

A little background:
28 years old, hubby is 30
PCOS is the only known fertility issue
Open tubes (normal HSG)
Husband’s semen analysis is normal
I ovulate successfully on Letrozole
I’ve had good follicle growth and strong progesterone levels
Recently did a monitored cycle with a trigger shot and had two mature follicles (only 1 monitored + trigger so far). Follicles were actually big (24 & 26 mm so we triggered, but it also could mean my follicles were getting too big before ovulating in my previous cycles, but since they were unmonitored I don't know for sure)

Had one chemical pregnancy in a non-letrozole cycle on month 1 TTC

My doctor’s plan is now:
Clomid 50 mg
Monitoring
Trigger shot

I’m curious if anyone here had a similar experience where Letrozole was clearly making you ovulate, but you still weren’t getting pregnant. Did switching to Clomid make a difference for you?

I’m feeling a little discouraged because I really thought it would have happened by now, but I’m trying to stay hopeful and trust the process.
Would love to hear your experiences—both positive and negative. ❤️

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u/Still-Passenger9941 — 1 month ago

10 dpo vvvvfl or indent? or nothing?

10 dpo test. This was using SMU as FMU was diluted. My eye keeps catching something but I definitely could be wrong

PS - You have to Zoom in 💕

u/Still-Passenger9941 — 1 month ago

8 dpo - am I delusional?

Currently cycle 9. First cycle with trigger shot. Trigger completely gone by 5 dpo. I'm not an early tester but been having weird symptoms and caved. I think I see a vvvvvvv faint indent/ shadow. Could it be a positive brewing? I know, I'm guarding my heart.

u/Still-Passenger9941 — 1 month ago

8 dpo (10 dpt) easyvvvvfl or delusion?

Cycle 9 here! First cycle with a trigger shot. I'm probably being delulu but I feel like I can kindaaaa see something.

I know, probably nothing there but I'm SOOO hopeful this cycle. It's the first time we truly got everything right. Pdg tests also positive so 🤞

u/Still-Passenger9941 — 1 month ago

Success with larger follicles? Triggered at 24 mm & 26 mm

Hi everyone,

I’m 28 with PCOS and currently on my 7th Letrozole cycle (9 in total) TTC baby #1 after a prior chemical pregnancy. This cycle was my first monitored cycle and I’m spiraling a little about follicle sizes/timing.

Protocol:
- Letrozole 7.5 mg CD 2, then 10 mg CD 3–6
- Follicles were 19 mm & 20 mm on CD 11. They didn't trigger me as they expected me to surge naturally
- LH stayed very low despite mature follicles
- CD 14 I went back to advocate for a trigger. Although I started surging (LH at 0.7) follicles measured approximately 24 mm and 26 mm
- No signs of ovulation yet on ultrasound (no collapse/free fluid)
- Trigger shot given CD 14 around 4:30 PM

We had intercourse on CD 11 and CD 13. Aiming for CD 14 (today) and CD 15 (tomorrow) as well

I’ve been reading mixed things online. Some sources say 24–26 mm follicles in PCOS/Letrozole cycles can still produce mature, viable eggs and may even be more ideal for PCOS than the "gold standard" of 18-22 mm. Other things I’ve read make it sound like anything over 22 mm is “overmature” and doomed.

Has anyone had success with follicles this size at trigger? Especially in PCOS or Letrozole cycles?

Would really appreciate hearing real experiences because I’m feeling pretty discouraged at the moment.

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u/Still-Passenger9941 — 1 month ago

Hi everyone. I'm currently in my 8th cycle TTC - which I know may not seem very long, but it's felt incredibly grueling especially because of the steps it's taken to get here and having a chemical pregnancy in cycle 1 of TTC.

A little background:
I'm 28, hubby 30.
I have PCOS. Managed with 2000 mg metform + myo inositol.
In December 2024, I did an open abdominal myomectomy for a 2 cm submucosal fibroid. Was cleared to begin TTC 10 months post surgery, so began trying in October 2025.
Cycle 1 in October, I got pregnant but it ended 2 days later. It was a chemical pregnancy. It was a natural cycle, so I ovulate on my own.
Before we began trying, hubby did a semen analysis. Everything looked good. His motility is also very high— like 98th percentile.
My thyroid function is normal. I have high AMH (typical of PCOS— 7.1).
Also tested LH, FSH, estradiol. All within normal range.

I'm freaking out as to why it hasn't happened yet, especially because we've done 6 letrozole cycles and I've read that doctors "expect" it to happen within six cycles.

Here is a breakdown:

Breakdown of TTC:

Cycle 1 - no letrozole
2 weeks post HSG
chemical pregnancy
LH peak: CD 19
Sex: CD 18, 19, 20

Cycle 2 - 1st letrozole cycle (5 Mg from CD 2 to 6)
LH peak - CD 14
Sex: CD 11 & 14
Not pregnant

Cycle 3 - 2nd letrozole cycle
LH peak - CD 14
Sex: CD 10, 12, 14
Not pregnant

Cycle 4 - 3rd letrozole cycle
LH peak - CD 14
Sex: CD 13 only (had the flu)
Not pregnant

Cycle 5 -4th letrozole cycle
LH peak - CD 14
Sex: CD 11, 12, 14/15 (technically 15 but at 12 AM)
Mucinex
Not pregnant

Cycle 6: 5th letrozole cycle (first at 7.5 mg - took from CD 3-7)
LH peak- CD 14 (evening this time).
Sex: CD 10, 13, 14, 15
Follicle scan: CD 10 - follicles at 17 mm, 14 mm, 12 mm
Not pregnant
8 dpo progesterone: 35.4 ng/ml

Cycle 7: No letrozole
LH peak- CD 16
Sex: 13,16,17
No mucinex

Cycle 8: 6th letrozole cycle. 7.5 mg letrozole. But first day (CD 2) I forgot and accidentally only took 5 mg. Other days did 7.5 mg
LH peak: CD 13
Sex: CD 9, 13, 14

I'm currently in the TWW for cycle 8.

Are there any additional tests I should ask for? Or further interventions? Or is this just a "be patient and it should happen" situation?

Grateful for any insight you might have 💕

reddit.com
u/Still-Passenger9941 — 2 months ago

Hi everyone. I'm currently in my 8th cycle TTC - which I know may not seem very long, but it's felt incredibly grueling especially because of the steps it's taken to get here and having a chemical pregnancy in cycle 1 of TTC.

A little background:
I'm 28, hubby 30.
I have PCOS. Managed with 2000 mg metform + myo inositol.
In December 2024, I did an open abdominal myomectomy for a 2 cm submucosal fibroid. Was cleared to begin TTC 10 months post surgery, so began trying in October 2025.
Cycle 1 in October, I got pregnant but ended 2 days later. It was a chemical pregnancy. It was a natural cycle, so I ovulate on my own.
Before we began trying, hubby did a semen analysis. Everything looked good. His motility is also very high— like 98th percentile.
My thyroid function is normal. I have high AMH (typical of PCOS— 7.1).
Also tested LH, FSH, estradiol. All within normal range.

I'm freaking out as to why it hasn't happened yet, especially because we've done 6 letrozole cycles and I've read that doctors "expect" it to happen within six cycles.

Here is a breakdown:

Breakdown of TTC:

Cycle 1 - no letrozole
2 weeks post HSG
chemical pregnancy
LH peak: CD 19
Sex: CD 18, 19, 20

Cycle 2 - 1st letrozole cycle (5 Mg from CD 2 to 6)
LH peak - CD 14
Sex: CD 11 & 14
Not pregnant

Cycle 3 - 2nd letrozole cycle
LH peak - CD 14
Sex: CD 10, 12, 14
Not pregnant

Cycle 4 - 3rd letrozole cycle
LH peak - CD 14
Sex: CD 13 only (had the flu)
Not pregnant

Cycle 5 -4th letrozole cycle
LH peak - CD 14
Sex: CD 11, 12, 14/15 (technically 15 but at 12 AM)
Mucinex
Not pregnant

Cycle 6: 5th letrozole cycle (first at 7.5 mg - took from CD 3-7)
LH peak- CD 14 (evening this time).
Sex: CD 10, 13, 14, 15
Follicle scan: CD 10 - follicles at 17 mm, 14 mm, 12 mm
Not pregnant
8 dpo progesterone: 35.4 ng/ml

Cycle 7: No letrozole
LH peak- CD 16
Sex: 13,16,17
No mucinex

Cycle 8: 6th letrozole cycle. 7.5 mg letrozole. But first day (CD 2) I forgot and accidentally only took 5 mg. Other days did 7.5 mg
LH peak: CD 13
Sex: CD 9, 13, 14

I'm currently in the TWW for cycle 8.

Are there any additional tests I should ask for? Or further interventions? Or is this just a "be patient and it should happen" situation?

Grateful for any insight you might have 💕

reddit.com
u/Still-Passenger9941 — 2 months ago