u/This_Astronomer_302

▲ 3 r/Autoinflammatory+1 crossposts

Pyoderma gangrenoseum on significant on head, 14 year old, clean bill of health, any ideas or thoughts on why he suddenly has this condition?

Case involves 14-year-old male, clean bill of health. Not diagnosed with any other health issues. Very active in sports. Dealing with a significant flare on head in the area of the initial site from 2023. The area we're currently dealing with was badly damaged from the initial case which took about 6 months to diagnose.

He has had it develop two other areas (skin and knee/thigh) very minor times. Steroids cream quickly resolved. We believe trauma/ fungal infections seem to be what triggers the immune response.

I am wondering if anyone has any thoughts as to why this could be happening now. He can have other significant wounds from wrestling but have no PG response.

Our family history did show other "autoimmune" responses in our household. Mother has hashimoto's (ongoing) and a case of severe vertigo, sister had a rheumatoid arthritis like spell from a likely viral infection (has not had any episodes like that since). All which occurred in 2023 at the same time the first PG episode occurred.

Are there any tests or Labs recommended? Any environmental things we should look at?

Located in the North Georgia area. Currently testing for radon. Drinking water from what appears to be a very clean, well close to spring head.

Any thoughts or ideas are welcomed!

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u/This_Astronomer_302 — 12 days ago