Statin or not? Looking for opinions from people with high Lp(a) and prior statin intolerance.
I’m 49M, 5’8” (173 cm), ~70 kg, exercise regularly, and eat reasonably well.
My numbers are roughly:
- LDL: ~140 mg/dL
- HDL: >50 mg/dL
- Triglycerides: <100 mg/dL
- ApoB: Moderate/normal range
- Lp(a): High (genetically elevated)
- Blood pressure, glucose, and the rest of my labs are good.
Family history:
- One first-degree relative had a heart attack around age 70.
- Otherwise, multiple siblings across two generations without premature cardiovascular disease.
I previously tried a statin but developed muscle pain, so I stopped it.
I’m struggling with the tradeoff. High Lp(a) seems to push many people toward lowering LDL aggressively, but the rest of my risk profile looks fairly good, and I don’t love the idea of lifelong medication if the absolute benefit is small.
If you were in a similar situation, what ultimately helped you decide? should I wait Reait for newer Lp(a)-targeted therapies?
I’m looking for experiences and the reasoning behind your decisions rather than direct medical advice.