12th International Conference on HIV Persistence & Eradication will take place in person on December 6-9, 2026.

ESCO Madrid October 20-21th update on Clover trial.

December 6-9 HIV conference. I can't imagine Dr. Jonah Sachs's recent HIV paper won't be presented.

January 8-10th ASCO complete update on the Clover trial.

Do you get the feeling Mr. Hoffman's going to Singapore in a few weeks with keys to the house with a note look what's coming.

Thanks for the house analogy MGK!

https://www.hivpersistence.com/

reddit.com
u/Vernon1211 — 3 days ago

A few thoughts

After all the time and research this board has done on Leronlimab we are now steps away from seeing the picture Doc envisioned.

I noticed more people popping in and commenting than the handful that normally keeps the board going. Great to see excitement building.

"Cytodyn is pursuing a flexible development strategy that includes both monotherapy and its "prime and pair" approach, where leronlimab is used to improve responsiveness to standard-of-care and immuno-oncology combinations."

This was from the Singapore post the other day. This is Doc's picture for the company. I see it as flexibility with the foundation being oncology. It would be nearly impossible for Cytodyn to go it alone as a mono therapy because they don't have the financial resources to do so.

Congrats to Doc understanding he's sitting on the upstream that most downstreams need either turn cold tumors hot or enhance the effectiveness of other companies meds. There are a lot of players out there that need us more than we need them.

We do need them as our foundation. We need the cash they're going to infuse into Cytodyn so Doc can move into the flexible part of his vision mono therapy. I always thought neuroinflammation and metabolic syndrome/diseases could be bigger than oncology. I haven't forgotten HIV. The more research I do the more I find the connection between CCR5 and the gut brain pathway. I don't think CCR5 over expression is the only pathway but it's a major one. What is apparent is chronic inflammation is the backbone to neuroinflammation and the different metabolic diseases.

The battle has yet to start on the SP side. I watched the SP yesterday because I thought we'd see a spike. We did see a spike in volume and 5% up swing in the SP. I thought perhaps this was the bottom. It still could be however every time the SP spiked it was slammed right back down. We ended up red for the day on 2x the normal 10 day volume. This has been the pattern for months. Shorts ok, short interest has gone up by a small amount. Sell the news , well this wasn't any news. Most likely manipulation by whoever and for what ever reason.

As we start to see the data it's important to see the SP also. The company has started marketing with Doc's interviews which has been well received by the biotech and investor communities. Spreading the word will be important also. The negativity out there needs to change to see the company grow and fuel the mono therapies. If anyone's in the biotech sub they know it's going to be a process of communication. A few tickers have been making the rounds the last few months. One well received the other well received but the reality of no infrastructure, no cash aka dilution, just started marketing because they just got a rare FDA appeal approval. It's a battle that Leronlimab will win on both the medical side and the investor side in time.

Just a few thoughts

Have a great weekend

reddit.com
u/Vernon1211 — 5 days ago

Strange issue

I have an older craftsman tractor with a 21hp B/S intek engine. 6 weeks ago I replaced the head gasket , new plug and oil change. Cleaned the fins for better airflow also. It started right up. Cut the lawn once with no issues and no more smoking. The next week it started to loose power with the cutting unit engaged. Disengage the cutting unit and wait for a few minutes and it started right up again. Continued to cut the lawn and after a few minutes it stalled. Let it rest and started it up again. I decided to change the ignition coil and a new plug again. It ran great for 3-4 cuts. I usually cut early AM or in the evening. Last Saturday I cut it around 2pm. Got 3/4 the way done and the same thing. It started to loose power. If I disengage the cutting unit power would come back. I shut it off let it sit for a few minutes then started it up and started mowing again. 10 minutes later the same thing happened started to loose power and disengaged the cutting unit. Power came back up shut it down let it sit. Started back up and was able to finish cutting the lawn. The outside temperature also decreased. Checked the oil which was fine.

Any suggestions as what's causing this intermittent loss of power?

Thanks

reddit.com
u/Vernon1211 — 16 days ago
▲ 6 r/lawn

Any clue what this is

First year I noticed this weed. Anyone know what it is and how to get rid of it.

Thanks

u/Vernon1211 — 2 months ago

Legacy firmware update

I have a legacy quad. Time was running out to update the firmware and did it this evening.

First I updated my 2nd generation Apple TV to the latest. That went fine with no issues. Tablo came right up as well as Netflix which I heard some were having audio sync issues. Then updated the Tablo. After reading about issues with the update I was nervous. The update went fine. I'm still using the legacy app.

Can anyone tell me what the difference is between the legacy app and the new app?

Best of luck to those running out of time

reddit.com
u/Vernon1211 — 3 months ago