ASXL1 mutation
My (23F) recent mutation testing showed positive for ASXL1 mutation around 7%. I haven’t seen anyone on here post about this so from everything I’m reading in studies I’m scared and confused. My Dr has suggested looking into a bone marrow transplant and referred me to a Dr to start this process. To be honest after hearing about how treatable CML is meant to be and easy it is to live with, it’s so so discouraging to have these results. I constantly heard that 90% of CML patients responded to tki. My bcr abl was 30% at 6 months and I was switched to asciminib. My dr made it seem like this is my last chance and then at 9 months we will do the transplant. so scared and confused. * i will add, I got a second opinion at a bigger hospital and well known cancer institute, and my Dr there told me he’s only done 1 BMT in 10 years for a CML patient. Its hard for me to grasp that my main Dr at home is suggesting BMT this soon but he seems concerned by this mutation