How would it turn out if the antagonists have Djinns, too?
Isaac and Co have their strength mostly from Djinns. The base classes without any djinn are pretty weak in comparison. I think it is Alex in GS2 that asks himself the question "Have they (Isaac and Co) become this strong in such a short time?" in regards to the death of Saturos and Menardi.
I found this always super weird because if you strip Djinn from the equations, Felix, Isaac and Co are pretty weak. In a casual playthrough you will make use of Djinn and they are actually part of the lore (however what their purpose is beyond stats is not explained iirc), but how would it turn out if the antagonists (Menardi & Saturos, Karst and Agatio) would use Djinn as well? They even have psynergy to drain Djinn so they are actually part of the story to some degree, too.
Imagine Saturos with 9 Mars Djinn and 9 Venus Djinn bound to him.