K99 Questions
Hi all!
I just got my K99 impact score back from NIA: a 34. My project is on cardiac aging and is not AD/dementia related. Going in, I didn't fully know (I am an idiot) that NIA effectively funds AD/ADRD out of a separate congressional appropriation, so non-AD basic aging projects compete in a much tighter pool.
My rough understanding is that AD/ADRD applications have historically been fundable at considerably higher (less competitive) impact scores (~32), while non-AD projects need to score much lower, roughly the high teens (~18). I know there are no hard published paylines this year, so this is approximate. A 34 for a non-AD project at NIA feels well outside the fundable range. The added pressure: my K99 eligibility window closes later this year, so I realistically have one more submission. I don't have my summary statement yet, so I can't judge the critiques, but I'm trying to think through the highest-probability path now.
The options as I see them:
Resubmit to NIA as an A1 and try to jump from 34 to ~18. Big improvement needed, same tough non-AD pool.
Resubmit as an A1 but request a change of primary institute to NHLBI (my science is fundamentally cardiovascular). Keeps the resubmission advantage, but the NIA critiques follow the application to the new reviewers.
Submit a fresh A0 to NHLBI. Clean slate, new reviewers, no prior critiques attached, but I lose the resubmission "bump" and can't formally respond to reviewers.
My gut says leaving NIA is smart, since NHLBI has no hard payline and historically funds K99s at more forgiving scores, so I'd need a smaller improvement. But I'm torn between options 2 and 3. Specifically: - If you've requested a change of primary institute on a K99 resubmission, how did it go? Did DRR honor it? - For a cardiovascular project, roughly where does an NHLBI K99 realistically need to score these days? - Given only one remaining shot, would you keep the A1 resubmission advantage or go in fresh as an A0 at the new institute?
Thanks so much. Any perspective is appreciated.