u/c12parsects

5 years later, I know what's wrong, I think

This might get a little long winded, I apologize in advance.

This all started 5 years ago for me. After I quit taking birth control and antidepressants, I started breaking out in hives, and then I started getting chest pains, and I got a little depressed again. I have brain fog and some dietary issues. Mostly when I get take out.

I've been researching the difference between DAO deficiency and HNMT deficiency. I tried a low histamine diet and taking supplements for DAO deficiency, did absolutely nothing for me, and made everything worse. I'm now looking into HNMT deficiency or slow HNMT. On my prenatal labs from my last pregnancy, my vit B was low, specifically B6 and B12. That was a year ago. Before I started looking into HNMT, I had started taking creatine because I'm nearing 30, and I work out a fair bit. It's been a month now on it, and it's made a difference! I'm only taking one zyrtec and pepcid a day when I was taking 2-3. I'm not waking up covered in hives, just a few patches or none at all. I'm still getting chest pains pretty regularly, mood swings, brain fog, and I get flushed. I feel like I'm more in line with the HNMT deficiency/slow HNMT.

I've been told that it sounds like my body can't detox the histamine properly, that my detox pathways are congested. I do believe that to be true, but I think there's other stuff going on. The same person told me I am probably stuck in dysregulation as well.

With all that being said, does anyone have any advice? I'm taking creatine, methylated vit B6 and B12, D3+K2, shilajit, liver support herbs with NAC, zyrtec, and pepcid. What blood panels or other testing should I look into? Can I truly heal from this?

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u/c12parsects — 3 days ago