CME and CAI's
I'm an OD.
I have an RP patient who developed CME bilaterally. Conventional pred and ketorolac did nothing, so I swapped the ketorolac for dorzolamide (after discussion with a retina specialist I know to confirm he prefers topical over oral CAI). A month later, the CME had improved about 50%. 3 months of treatment and one eye has returned to normal, the other is still kind of lingering. But reviewing literature, I really have only found articles that discuss CME secondary to RP and the use of topical CAI.
There does appear to be some studies that look at efficacy of oral acetazolamide in CME and other macular edema types patients. In the same overview paper listed, it also lists topical CAI in macular edema, but most of the papers appear to mainly focus on RP-CME.
My question for the forum - does anyone have experience utilizing topical CAI's on patients with CME post membrane peel, post cataract, post RD repair, etc.? Given topical would be generally quite safe, I have to imagine that there's some articles out there that outline this that I am not seeing.