u/flockofduckz

Hi all,

Mounjaro has in the past been pretty effective for me for IWL, T2D, food anxiety, and metabolic dysfunction, but the side effects are becoming intolerable. About 12 hours after injection, like clockwork, I experience severe bone-crushing fatigue for at least a day and a half, usually two.

This isn't from lack of hydration, nutrients, or protein. I eat full and nutritious meals. The fatigue seems to be a direct reaction to the surge of medication in my system before my body adapts. I suffer from moderate ME/CFS and already experience bouts of severe fatigue, so with the added mounjaro fatigue it's overwhelming!

I have had to take several breaks from Mounjaro due to the fatigue and am currently trying 7.5mg every 10 days as I couldn't cope with 2 days of shot fatigue per week even at 5mg. I am only managing to maintain weight on this dose and dread going up.

For this reason I'm tempted to try a daily medication instead as it will remain at a steadier level in my system and hopefully be less of a shock to my body.

My options in the UK are:

Saxenda/Liraglutide daily shots

Foundayo pill

Wegovy pill

I have experienced very few GI side effects so I imagine I will tolerate a pill. Despite my energy limiting disability I think I could manage daily shots or the finickyness of the wegovy pill if my GLP fatigue lessened. I would be happy with slower weight loss or even maintaining if I could just avoid the crushing fatigue.

What I'm stuck on is which to try next - each one seems to have its drawbacks and there are reports of fatigue for every GLP med.

The cost is less of a concern as any of the above would be cheaper than Mounjaro.

If you were in my position, which would you try next and why?

Hi all,

Like many people here I have found benzos (specifically lorazepam/ativan and diazepam/valium) to be helpful when used carefully and sparingly to avoid PEM in overstimulating situations.

So far I've been obtaining these by less than legit means because UK doctors are very reluctant to prescribe benzos.

Can anyone link to any good studies or resources to show my GP about the use of benzos for ME?

I would also be keen to know if anyone has had any success getting these prescribed for ME in the UK.

Thanks!

This might be a dumb question but I genuinely don't know the answer. We have a mortgage offer with YBS and have now seen that other lenders have (slightly) better deals. Do lenders ever adjust their rates to match their competitors or are the rates offered set in stone?

Is it worth asking YBS for a lower rate to match other lenders or should we just start a new application with the lender who has the best offer?

We are not in a time sensitive position due to delays in the conveyancing process that will take a while to resolve.

Thanks!

TL/DR: I use a chore sharing app (Sweepy) to manage the schedule of tasks assigned to my carer/personal assistant. It removes the mental load of delegating tasks every shift

Hi all, I wanted to share something that has helped me maximise the benefit of the care/assistance I get.

I'm moderate and fortunate enough to have 5 hours of personal assistant support a week to help me with household chores. I split this over 2 days per week.

Previously when I had a PA, I would make an assessment of the chores that needed doing and write them down on a scrap of paper for my PA to cross off. I think at the time I was too fatigued and foggy to improve this process and make it more efficient, even though it cost me precious energy to delegate in this way.

A friend suggested I look into chore sharing apps, which I didn't know were a thing! They are usually used by couples/housemates who want a way of organising and delegating chores fairly. It turns out they also work if you're getting someone else to do your chores. They would be really useful if care/support is divided between multiple people too.

I downloaded a few to test their functionality and interface and settled on Sweepy. I like it because it clearly displays notes below each task, allowing you to add specific details about how you want something done.

You can set up regularly occuring tasks. I have a bunch of core tasks set up to be completed every care day (laundry, washing dishes, cleaning kitchen etc) and other tasks set to be weekly, fortnightly, monthly etc.

Adding the less frequent tasks onto a schedule means I no longer have to scan around to see what needs doing - I just guestimated how long I should leave between each task and now I can tweak it accordingly if I happen to observe something needs doing more or less frequently.

It takes energy to set up a system like this, but it was very much a 'set and forget' thing - I didn't even need to look at the app for the first couple of months as I was confident that as long as my PA was tackling the daily tasks and chipping away at the other tasks, everything would fall into routine. I can now keep interactions with ny PA to a minimum when I don't have the energy to engage - a huge win!

I know not everyone has the privilege of support at home, but I wanted to share what works for me. Feel free to share what works for you too.