u/formanz

Hello, I’m new to quality control and I basically don’t know any established procedures yet.

I work in a small lab with a single GC/MS system and only a few samples per day. Our current QC practice is to run one QC sample every morning and simply check whether the retention times and responses of all compounds are roughly the same as the previous day.

I’ve started to suspect this is not the best approach, especially because our QC mixture contains compounds that could be used to monitor isotope ratios and peak symmetry, not just RT and response (based on some research).

I tried to look up QC procedures, but most of what I found were very general descriptions. Since I don’t really know how these steps should be implemented in practice, I’m trying to understand what real, day‑to‑day QC workflows look like in other labs.

• Do you have any automated statistics or scripts that evaluate your QC runs?
• Do you calculate everything manually?
• Do you use multiple concentration levels in your QC standards?

We rarely do quantitative analysis and we only analyze a few samples per day, with several different methods that all use the same column and matrix. Because of that, I feel that measuring one QC sample every morning plus a few additional QC samples every couple of weeks should be enough for us.

We use Agilent MassHunter (Quant‑My‑Way and Unknown Analysis). Is there any way to set up a script or automated statistical analysis so that MassHunter can generate a QC report for us automatically?

Viz title. Hrozně mě zajímá, jak vidí lidé, kteří silně šilhají. Znám jich několik a většina z nich kouká fakt úplně mimo, ale vím že koukají přímo na mě. Někdo šilhá dovnitř a někdo ven. Vidí stejně nebo rozdílně?

Mají něco jako panoramatické hledí a vidí víc než my? Nebo naopak mají díru uprostřed výhledu. Diskutujme prosím 😀

Sorry za hloupý dotaz, ale fakt mě to zajímá 😀

Hi everyone,

we would like to buy some standards of synthetic cannabinoids and NSOs, but Cayman is quite expensive for us (at least for now).

Do anyone have experience with LGC Chemicals distributor and brands like TRC or LoGiCal (sold by LGC)?

Any comments will be appreciated, thank you!

Have a nice day!