Time for even more chemicals to try and fix myself! (This time its aticaprant, also my experience on agmatine and sarcosine)
Unfortunately I have to say that both agmatine and sarcosine suck donkey ass.
For NMDA antagonists, I completely forgot that lamotrigine (which is somehow adjacent beacuse of the decrease in glutamate) made half of my face droop in 2023, I only remembered that it made me weak so it was a lightbulb moment the day I took agmatine and I started feeling that its so much harder to keep the right side of my mouth closed, as someone who had a father with ALS I'm not gonna mess around with that shit anymore. Fortunately, the symptoms stopped pretty quickly.
And as for sarcosine - it made me slightly more energetic but energy is not really a problem for me anymore, in terms of anhedonia it did nothing. Unfortunately it gave me anxiety, especially when coupled with NAC, but the effects seemed to build up and I had to decrease the sarcosine dose a lot but the anxiety and ruminations always came back after a few days so I stopped taking it. Not the worst thing I've taken by far, but didn't really do anything good for me.
Next up is aticaprant - inspired by u/Turbulent-Place-6723 who seems to have vanished off the face of the Earth, I've spent a good chunk of money on buying it from seller that really, really wants me to get addicted to the free sample of some heinous research chemical that came with all of my purchases there so far. But besides that they're legit lol. While I know the most recent studies weren't optimistic, kappa opioid receptors are one of the few things I haven't poked yet and I'm finally stable enough again to withstand some shitty side effects without completely losing my mind. Wish me luck!