u/lilfairyfeetxo

The FDA finally approved use of pritelivir for immunocompromised carriers. We need to figure out how to pressure Asahi Kasei, AiCuris, and VIDS Research to complete the phase 3 trial including immunocompetent carriers that they canceled. I refuse to sit and wait until the next HPIs hit the market, which won't be until approximately 2029 or likely later, or for them to twiddle their thumbs until they find it's pleasing to them to expand their customer base.

What can we do? Mass email all three of them? Emphasize that they are foregoing profits that could be made from maximizing sales volume? There is momentum with this approval, I want to strategize how best to make use of it.

Thank you everyone, and hope you are doing okay.

Hello! I believe our community’s #1 priority for the present is working on affordable pricing for pritelivir. I fully understand the doubt, frustration, exhaustion, and skepticism towards the potential of activism to create the changes that this community has been waiting on for decades. In an effort to encourage greater hope and confidence that we can actually make affordable access happen, I am sharing some brief info on hugely successful past advocacy campaigns for other drugs and treatments, and some strategies we can put into action.

—AZT (azidothymidine) for HIV/AIDS: U.S.
Mar 1987 - Sep 1989: 2 price reductions, each 20%, outcome: annual cost reduction from $7,000 - 10,000 to $6,400

—Second-line drugs for multidrug-resistant tuberculosis: International
Late 1990s - Jul 2001: single treatment course reduction from $10,000 - 19,000 to $2,500 - 3,600

—Insulin: U.S.
2014 - 2023: Medicare cap on co-pays at $35/mo, major manufacturers committed to 70%, 75%, and 78% list-price reductions

—List of strategies to achieve this:
Government price negotiation, generic competition, public pressure & mass activism, patent reform & compulsory licensing, public/nonprofit drug manufacturing, expanding insurance/public coverage, importation & international reference pricing, antitrust enforcement, hospital & treatment price regulation, organized purchasing coalitions

[Disclaimer: This information was gathered using ChatGPT. I acknowledge the ethical issues surrounding AI, but I also have a busy, stressful life, and this use of AI provided me with tons of useful information so much more rapidly than traditional searching.]

If this has you a little more excited and hopeful about getting active, comment or send me a message and let me know if you are interested! This group chat isn't meant to add any pressure or stress to anyone's lives. You can join in and browse our discussions whenever and in whatever capacity is best for you. Also, if you would like to share, let me know what your main ideas for action are and what you think this community should prioritize the most.

~Thank you! Looking forward to discussing!~

Hi, apologies in advance for a noob outsider post!

My partner and I are doing a short getaway in a stationary RV. I purchased battery operated smoke/CO detectors. Does anyone have ideas or recommendations for how to place or rig a detector that is high enough and requires no harm or alteration to the RV interior?

Thank you!

Hi, apologies in advance for a noob outsider post!

My partner and I are doing a short getaway in a stationary RV. I purchased battery operated smoke/CO detectors. Does anyone have ideas or recommendations for how to place or rig a detector that is high enough and requires no harm or alteration to the RV interior?

Thank you!

EDIT: I'm not sure if they have a detector, I chose the most reliable one I could find, and I'm worried about asking more safety questions on top of what I've already asked the host.