u/rubzir1

Is there a connection between IgA deficiency and the severity of the disease?

My diagnosis is severe psoriatic arthritis. I have inflammation in many joints, along with widespread psoriasis all over my body that barely responds to treatment. I am currently being treated with Remicade, which helps my joints a lot, but unfortunately it has almost no effect on my skin.
In my blood tests, my doctor found that my IgA levels are extremely low (IgA deficiency) . He thought this might possibly explain why my condition is so severe.
Anyone else here has an IgA deficiency?
Do you feel that it affects your PsA or psoriasis?

Also, has any biologic treatment helped your skin, especially if your psoriasis was severe or widespread?

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u/rubzir1 — 1 day ago

Has Anyone Tried a Combination of Two Biologics?

I have had psoriatic arthritis for more than +5 years. I am currently taking Remicade for my joints, and it is working very well for me.

Unfortunately, it has almost no effect on my skin, and my psoriasis is really bad right now. I do not want to stop or change the medication because it helps my joints so much, but I am wondering about adding another biologic specifically for my psoriasis.

Has anyone tried using two biologics at the same time, one for arthritis and one for psoriasis? Or is anyone currently being treated this way?

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u/rubzir1 — 1 day ago