r/Psoriasis

I've been on Skyrizi for about 3 years now. My psoriasis has only ever been on my scalp, no joint pain or other areas involved. Curious to hear from others who've paused or stopped it (insurance issues, side effects, wanting a break, etc.).

A few questions:

• How long were you on it before stopping, and how long did it take for symptoms to return (if they did)?
• Did the flare come back as bad as before, worse, or milder?
• If you restarted Skyrizi after a gap, did it work as well as the first time, or did you notice reduced effectiveness?
• Roughly how long was the gap before you restarted?

Also curious — has anyone tried stretching out the interval between doses instead of stopping completely? Like going from every 12 weeks to 13, then 14, then 15, etc., pushing it out a bit more each time rather than cold-stopping. Did that work okay, or did symptoms creep back once you went past 12 weeks?

Part of why I'm asking: I don't love the idea of being dependent on a medication long-term, and I'm a bit wary of staying on an immunosuppressant as I get older (infection risk, whatever else comes with aging on a drug like this). So I'm trying to figure out if there's a realistic path to less frequent dosing, or if that's just wishful thinking for how this drug works.

Trying to get a sense of what's realistic before I consider changing up my own dosing. Appreciate any experiences you're willing to share.

so i’m not actually sure if this is connected to my psoriasis but i’ve developed all these bumps around my thighs, they seem like ingrown hairs but I don’t shave there so i’m not sure how that would happen. I exfoliate often and there hasn’t been any change in products. i’ve been on biologics for about 6 years and I noticed the bumps about three months ago.
Has anyone else with psoriasis experienced this or is this a different issue?

Hello! I was prescribed Icotyde for my plaque psoriasis and PsA 2 weeks ago. I took my first dose today. I want to keep a log of my experience with it. So, I'll update here weekly. I may include some photos of progress eventually.

All I’ve heard since diagnosis is about the impact of diet but after months of paying attention I’m really not convinced my diet has anything to do with it. It gets worse randomly when I’ve done nothing “wrong” with my diet and then will get better after I spend a weekend drinking and eating poorly. I had already suspected that stress was my biggest trigger and I’m becoming more confident in that. Is anyone else in a similar boat where diet just doesn’t factor into the disease for them?

I have had psoriatic arthritis for more than +5 years. I am currently taking Remicade for my joints, and it is working very well for me.

Unfortunately, it has almost no effect on my skin, and my psoriasis is really bad right now. I do not want to stop or change the medication because it helps my joints so much, but I am wondering about adding another biologic specifically for my psoriasis.

Has anyone tried using two biologics at the same time, one for arthritis and one for psoriasis? Or is anyone currently being treated this way?

Suspected palmoplantar psoriasis, diagnosed at a university clinic in Germany. Started over a year ago. First they thought it was fungal and gave me antifungals. Never got a biopsy or scraping to this day, so officially it's still just "suspected". Fun.

Since then I did everything by the book.

Antifungals at the start, did nothing. Then mometasone for over 4 months, worked while using it, all came back worse after stopping. Tried Wynzora, my skin reacted badly so we stopped that too. Then the university clinic gave me a proper protocol. Salicylic acid 5% every night to descale, cotton gloves and socks while sleeping. Then calcipotriol daily for weeks. Now tacrolimus alternating with the calcipotriol. On top of that urea creams, Cicalfate, CeraVe, liquid bandage for the cracks. I even bought a narrowband UVB lamp with my own money because clinic phototherapy 3 times a week is impossible with a job and a kid.

Result after a year of this: skin cleared once, came back during active treatment. Now it's spreading. My second foot got a fresh plaque this week while I'm literally mid treatment. New spots on fingers that were never affected before.

And the doctors? Everyone says something different. My GP refused to prescribe anything. My private derm doesn't even agree with the clinic's protocol, says tacrolimus is off label for psoriasis. The clinic works in 3 month cycles and you can't reach anyone in between. So basically I'm managing a multi phase treatment plan alone at home.

I know it's chronic. I know there's no cure. I know biologics exist somewhere at the end of a bureaucratic tunnel of "documented topical failure".

Honestly I'm fed up and really close to just quitting every treatment. At least then I know where I stand. It won't heal, fine, but no more false hope every single evening with the gloves and the creams and the waiting.

Anyone here who just stopped everything? What happened?

TL;DR: 1 year of suspected palmoplantar psoriasis (never confirmed with biopsy). Tried everything: antifungals, 4 months steroids (rebounded), Wynzora (reacted), salicylic acid, calcipotriol, now tacrolimus, plus a UVB lamp I bought myself. Skin cleared once slightly, came back mid treatment, now spreading to new areas. Doctors all disagree with each other and I'm managing this alone between 3 month appointment cycles. Ready to quit all treatment. Anyone just stopped? What happened?

I'm 16 and like anyone my age...i wanna do skincare... I'm just confused whether i should do it or not. I mean i have Psoriasis, should i focus on my other skin problems while keeping Psoriasis in mind. Or just fuck skincare and only use moisturizer and stuff for my psoriasis.

I have 5% naicinamide, 2% salicylic acid and 10% azelaic acid.+ Cerave cleanser and mineral based sunscreen.

Are these products too harsh or fine cuz i did my research and everything.

(Sorry if i sound like a brat..trust me I'm not🐈‍⬛)

After 1 year on Skyrizi, I can say that this drug has changed my life. Scalp psoriasis took over my life about 10 years ago.

I tried EVERY SINGLE THING to avoid medication: Xtract laser, UVB handheld device, Clobetasol shampoo, Clobetasol solution, Zorayve foam, weird oils from Amazon, Vitamin D cream, no gluten/dairy, no carbs...

Now, I don't even think about it. I woke up one day and realized that I don't think about it any more.

I can wear black and not be covered in flakes. I am not self conscious about getting my hair done.

I know we focus on skin but the mental FREEDOM from psoriasis has truly been amazing. I didn't realize how ashamed and self conscious I was — and how I was holding back from relationships and experiences because of this.

Hi there, which device/brand is considered gold standard for at home UVB light therapy? Did you need an Rx from your provider?

Have any of you used any with results? Has anyone had success?

Hello all,

I'm finally prescribed medication that isn't just ointments and I feel awful. I'm going to have to stop on the advice of my derm (apremilast) due to dehydration, GI issues, appetite effects etc.

The next treatment is at risk of infec-tion, poor immune system, mouth ulcers....

Then biologics don't sound great either...

Is it worth it? Or just live and suffer with psoriasis or have to suffer from the medication?

I'd love to hear people's experiences as we are all different. But looking for hope or advice to bail out and not waste my time feeling awful.

I recently started on Skyrizi and after the 1st loading dose I noticed a huge improvement but it only lasted like around 3 weeks, not even to the 2nd loading dose. I had no improvement with the 2nd loading dose or the 1st of the 3 month maintenance dose. I still have like 2 months before next maintenance dose. Does this mean it's not likely going to work for me and the first couple weeks were just a fluke? Skyrizi is my first biologic after 5 years of trying different creams and phototherapy with minimal success.

I’ve been dealing with a bad scalp psoriasis flare for a couple months and I’ve finally got it under control. However, about 1/4 of my hair has fallen out. I’ve stopped using pretty much all of my hair care products other than a hair mask 2-3x a week in fear that it would worsen my flare up. My hair is down to my butt and is super dry. I stopped using any oils, treatments or detanglers other than the hair mask. Does anyone have any tips or products that they use on their hair (for strong/healthy/soft hair) that doesn’t seem to worsen psoriasis?

Hi there,

I had a hair transplant a few days ago and am now on day 4. I have a form of psoriasis on my scalp that I treat with clobetasol, super-high-potency topical corticosteroid, but have not used it since before the transplant. Was wondering if anyone here had an experience where they could not use clobetasol initially and when during the process it was safe to go back on it?