u/scarychary

Hello! 19F with ADHD / autism combo, strongly mirroring the symptoms of excessive glutamate much like many posters here.

I hear a lot about people finding success with taking GABA, but on here the most common recommendation I see is to take Glutamate antagonists / GABA agonists instead of just taking GABA directly. Why is this? I'm struggling to search for an explanation, with the only I've been able to find being that GABA doesn't cross the BBB but that's become more and more disputed over time.

I hate managing a huge stack of supplements and if I could (being idealistic here) just take GABA as a single supplement that would be nice, as I also react weirdly to a lot of the suggested alternatives (l-theanine + every form of magnesium I've tried makes me feel SO groggy, NAC might interfere with my ADHD stims unless I take it at a rly specific time).

Please excuse my lack of knowledge and if it shines through in my descriptions. Posting this here to learn, as all of the information is really intimidating at the start.

hey guys, i'd greatly appreciate anyones input on the following:

i'm getting jaw surgery hopefully this year (lefort 1 + bsso) to correct a class 2, but i'm stumped on the options i've been given to prepare my teeth before surgery

I have a big overjet of 1cm and my teeth protrude out a lot. my ortho + surgeon have informed me that this protrusion must be fixed PRIOR to surgery, with one of the two options:

premolar extractions to create space to bring down the proclination of the teeth
teeth shaving (ipr) to create space to bring down proclination of the teeth, combined with a bit of clockwise rotation (i think my occlusal plane is extremely flat so this protrusion is probably a bit skeletal, so CW is indicated?). I am told that this option may NOT be enough to correct it and achieve an ideal bite in the end.

in both cases, i'll be getting a segmental lefort to widen my palate, as the shape is too narrow for my bottom jaw.

I'm a bit adverse to option 1 because I don't really want to lose teeth, but I'm aware that plenty of people get good results from it (i'm unknowledgeable on how extractions aren't "bad" when combined with djs, i'd like to read a good resource on that if anyone has one).

option 2 initially sounded less invasive but scares me as I have issues with weak enamel, and a lot of my family members who have gotten IPR on teeth say those teeth are super sensitive now. because my proclination is so severe i'd say my ortho will try to shave off as much as he can, which raises a really big red flag for me given the above.

option 3? i thought if i'm getting a segmental lefort anyways and need more space to reduce this proclination, then maybe mse (i'm 19F) would do the trick, as it's minimally invasive and would avoid more invasive cuts from the segmental during surgery. I asked my surgeon via email and all i got in reply was "a palate expander is not an option given the clinical presentation." interesting, given the fact that surgical expansion is in my treatment plan.... I would really like to book another appointment with her just to understand / discuss this, but i'm not sure if thats standard as a jaw surgery patient to do (appointment just to ask questions ?? 😭 im only 19 and managing all of these appointments and decisions on my own so please no judgement)

I just want whichever option will give me the best and healthiest result but i'm lost on what to do here despite researching so much prior.... does anyone have any guidance at all? of course i dont trust reddit over specialists, but contacting them can be slow and hard, and everything is so much more anxiety inducing when it's a decision for your own surgery :[

new to nootropics and a bit confused about GABA