I know the GBM kills people by putting pressure the brain resulting in degradation of it's fucntion. I wanted to undertand how the end will be. Will they die in pain or peaceful? Will it be a seizure or organ failure? Will it the brain stroke?
My father just became bed ridden today after his recurrence. He is saying and we also undertood that the end is near. But we don't know how.
My dad was diagnosed with GBM WHO Grade 4 13 months ago. He underwent biopsy extraction after first the tumor was discovered in the MRI in the right parietal lobe. The neurosurgeon suggested not to go ahead with surgery for debulking of the tumor. He said it may result in permanent damage of motor functions of left limbs. I went to 3 other neurosurgeons and all said just to go ahead with the radiation + chemo. All said the tumor was small ~4 cm.
EBRT of 30 cycles with Temozolamide was done and then for every 28 days we had Temozolamide 300 mg upto 8 cycles. He was ok all these days and one day after our great trip (15 days travelling around the country) he started falling everyday all of a sudden. Left leg became very weak. We had an MRI after 11 months from initial MRI (the radiation oncologist didn't prescribe one even asking multiple times).
This time the original tumor became half ~2cm, but the two new tumors at corpus callosum and right lateral ventricle. At this stage, the swelling was also very heavy and they started steriods. And he was given a live expectancy of 6 months at this stage.
We again went to some neurosurgeons and all adviced palliative chemo. After discussing with him all these, he is asking not to go ahead with the chemo and he wants go away as soon as possible as he is burdening us. I convinced them somehow and scheduled the chemo appointment. Just as we are going to the first chemo cycle, he tripped and fell again. I don't know what happened but this time he became completely weak. He couldn't move his legs (btw no pain or anything. He just couldn't move them). we had to carry him around in a wheelchair. He is not at all cooperating with the treatment and askimg us to kill him somehow. I feel like he lost the will to live finally after coping up with it for all these months. My mom too, saying we can stop these treatments as we won't be able to move him around to hospital if he became bed ridden.
I'm at lost now. I want to continue the chemo hoping it helps with the brain swelling and gives him some relief during his final days. But I'm also not sure what to do. There are so many regrets i had in my mind, if we had taken him to a better neurosurgeon who would directly debulk instead if biopsy, may be he can live more freely. May be if we have taken the MRI before, we would identify the new tumors beforwhand and treat them. May be if we had started the second line treatment few weeks before he wouldn’t become bed ridden. Idk all these thoughts are eating me.
Diagnosis: Glioblastoma (WHO Grade 4) recurrence
Treatment: Targeted Chemotherapy
Drugs used: Bevacizumab 800 mg (\~20k) + Irinotecan 300 mg (\~3k)
Originally the cost should be 70k + 15k. But as we are getting treatment at Tata Memorial Cancer hospital, we are getting discounted medicines.
There is a system here where all patients have smart card and we have to top up that card and pay using it.
If i want to raise a health insurance claim from icici lombard, how should i submit the bill payments? The bills will have mode of payment as smart card. Do i need to include the smart card statement as well? If i include, how will they identify the specific transactions used for this treatment? Please let me know if anyone have any idea.
Treatment: Targeted Chemotherapy
Drugs used: Bevacizumab 800 mg (~20k) + Irinotecan 300 mg (~3k)
Originally the cost should be 70k + 15k. But as we are getting treatment at Tata Memorial Cancer hospital, we are getting discounted medicines.
There is a system here where all patients have smart card and we have to top up that card and pay using it.
If i want to raise a health insurance claim from icici lombard, how should i submit the bill payments? The bills will have mode of payment as smart card. Do i need to include the smart card statement as well? If i include, how will they identify the specific transactions used for this treatment? Please let me know if anyone have any idea.
I am a working professional from India and i have good knowledge of english and i can handle a conversation. But I am not very fluent. I trouble to choose words and also i use very basic words to express my thoughts. I want to speak English fluently and with good vocabulary. I have learnt all the grammar and everything related in my childhood, but i don't see using all the things.
I tried duolingo, but all it teaches me is basics. I added myself as intermediate english student, but all i see are the questions I can answer easily. Do you guys know any other such apps that helps me refine my english speaking skills?
Hey guys, I want to travel alone to some quiet place in india. In recent years, all travel places and treks became very crowded. Do you know any treks in Uttarakhand or Himachal that are known to very less people and we get to enjoy the nature and experience without feeling crowded?
Hii guys, I am planning for kedarnath and one other basic himalayan trek (not planned yet) in the month of june and september. I want to buy good trekking shoes but unable to decide. I first decided to buy decathlon, but the basic waterproofing started from 5k. I am hesitating a little as i won't be wearing those shoes often as they are only for trekking (i have other shoe collection for daily and occasions).
I have explored budget options like in wildcraft, asian, ctr and boldfit, but didn't find proper waterproofing. They are good for that price range but my mind again playing games. I am unable to decide which shoes to buy. If anyone of you have experience, let me know which are the best shoes for trekking under budget.
Hii guys, I am planning for kedarnath and one other basic himalayan trek (not planned yet) in the month of june and september. I want to buy good trekking shoes but unable to decide. I first decided to buy decathlon, but the basic waterproofing started from 5k. I am hesitating a little as i won't be wearing those shoes often as they are only for trekking (i have other shoe collection for daily and occasions).
I have explored budget options like in wildcraft, asian, ctr and boldfit, but didn't find proper waterproofing. They are good for that price range but my mind again playing games. I am unable to decide which shoes to buy. If anyone of you have experience, let me know which are the best shoes for trekking under budget.
I started hooking up with a friend back in college. At that time, it was pretty mutual. we’d kiss and suck (no anal)
Now, years later, whenever we meet up, he’s completely against kissing. He’s a bottom and wants me to suck him, rim him, and fuck him, but the moment I ask for a kiss or even a blowjob in return, he flat-out refuses. His attitude is basically “serve me or leave it.”
I think he’s deep in denial about his sexuality, but honestly, I’m in the same boat. We’re both closeted, and he’s literally the only person I can talk to about gay stuff or do anything with. Because of that, I’ve been going along with his one-sided demands every time.
I’m starting to feel used and resentful. Should I continue putting up with this one-sided thing, or is it time to walk away?