Estradiol Gel Anti-aging
I’m 40F and somewhere in the peri → menopause transition. I had a hysterectomy at 31, and I’ve been on HRT for a couple years now.
For the longest time, I applied my estradiol gel to the inside of my thighs. Then I got lazy and started applying it more on the outer thighs instead. After a while, I noticed the skin on the outside of my thighs looked… different. Smoother, firmer, tighter, noticeably less cellulite. It honestly caught me off guard.
Naturally, I went full rabbit-hole mode and started reading about women experimenting with estradiol gel or vaginal estrogen cream on facial skin. I know this is completely off-label/experimental, but curiosity got me.
So I cautiously tried a tiny amount mixed into moisturizer on my face and now I feel like I’m losing my mind a little because my skin looks SO much better. Plumper, firmer, more hydrated, more radiant overall. And I’m someone who spends a ridiculous amount of money on skincare and medi-spa treatments chasing the “holy grail.” Nothing has given me results this noticeable this quickly.
I genuinely don’t think this is placebo.
Has anyone else experimented with topical estrogen for skin quality? What were your results? Any downsides or things you noticed long-term?