u/somecanadian13

Hi community. About to take my 7th dose of tirzepitide, third at 5mg.

When I started, the satiety cues were definite. It was a big change from my usual.

I dropped inflammation weight in the first week and the number was surprising. The weight loss continued over the four weeks at 2.5mg in a more reasonable way. My PCP and I decided to titrate to 5mg.

Since then my scale number has bounced around the same number +/- a couple lbs. I haven’t had any shifts in pain response, and I’m feeling inflammation creeping back.

I also don’t have the same satiety cue - I continue to eat a smaller portion than pre-meds, but I find myself getting snack attacks again, especially in the evening when I’m watching tv.

I absolutely don’t want to “diet”, and find myself rebelling against “eating healthy” (to be clear, I tend to cook a lot and eat a balanced nutrition mix).

At the same time, I’m feeling some failure that I am on a higher dose and numbers aren’t moving.

Pain prevents me from traditional working out (really hoping for some pain relief as I continue).

I know that I need to be patient and let my body adjust to the meds. I know this is a long road. But I’m feeling shitty.

Hi community. I’m on my second shot of Mounjaro at 5mg. I haven’t seen any movement in my scale numbers (bouncing around the same numbers +/-). I’m also feeling more inflammation (now that I know what it feels like).

I logically know this is a process and not necessarily linear. I logically know that it will take another 2 shots before my body has the full minimum clinical meds on board. I logically know that these are early days and I’m doing the long haul for a bunch of improvements in my health and mobility.

Yet here I am, bummed. IWL isn’t the primary reason for me to be on the drug, but it’s not unpleasant. And little alarms are going off because I’m bummed that the numbers aren’t moving down - it feels like a slippery slope into diet-town. This morning I thought about lower calorie foods and then I got sad - too familiar - I spent too many years eating that way.

I think I am asking for support and encouragement. I am not asking for advice around macros or calories or anything food-related, if that makes sense. Thanks peeps. ❤️

I took my fourth beginner dose of Mounjaro today. I notice that the initial “don’t want snacks” effects are not nearly as potent as they were after the first dose. It’s still different than before I was on the meds - I have smaller portions than I used to, I experience hunger differently, there isn’t the same urge. I’m talking with my PCP for the first time since I started, next week. I think (?) I want to go up a level, partly because of the return of the snack attack (which is understandable- I am under an enormous amount of stress), and partly because I want to see if a higher dose will impact my chronic pain. What are your markers to increase?

Hey community. I’m in my second week on Mounjaro. In the first week I dropped on the scale - I am guessing it was water weight/inflammation.

I haven’t owned a scale in years. It brings up a lot of shitty diet culture programming for me - the data doesn’t feel neutral.

For me, I opted into this medication to impact pain and inflammation. If there’s weight loss I want to think of it as a byproduct (so that I don’t get sucked back into toxic stuff in my brain).

My doctor asked me to check my weight regularly while taking the medication. So I bought a scale.

My problem is I am getting obsessive about checking. My logical brain knows that the likely progress of any weight loss is slow and steady, and likely with plateaus. My emotional brain is anxious for proof that the drug is working.

Anyone else feel like this? What are your strategies?

I posted earlier and violated one of the rules of this sub. I’m really sorry - this space is very valuable to me. I’m new to Reddit and wasn’t thinking. For anyone who was triggered - please know I have edited the post in question and I will do better in future. Your safety is important to me.

Edit: thank you to the mods of this community for rightly asking me to edit this post and remove the number originally included. I am sorry for the violation of the safety rules here, and appreciate the opportunity to adjust.

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I took my second dose of Mounjaro today. My PCP asked me to take scale measurements. I am down a surprising amount. (I decided to try trizepitide for inflammation and pain management. WL is a byproduct.)

There’s this absence that is hard to explain to people who haven’t been on this drug. I guess that’s the drug acting on the brain?? Also, for the very first time in my entire life, I heard my body say it was full. Like, mid bite. And it was so clear a signal that I couldn’t eat anything else.

I notice that there’s big gaps that used to be filled with snacks and drinks. I still have snacks and drinks, to be clear - just am done sooner, which is brand new. Also brand new - my body is asking for water. Even before coffee.

I feel very lucky - so far the only symptom (aside from a small amount of discomfort at the injection site) is a headache.

I was so anxious before my first dose (thanks to this community for the support). Now I’m not anxious, I am just feeling like it’s WEIRD.

I started Mounjaro today. I also have been managing visual migraine, which started before I injected. It is like looking through an electrified kaleidoscope, and is disorienting.

After the injection, I felt a warm flush. The actual injection was not a problem. The flush feeling was odd but not unpleasant. I’m aware of the injection site but it doesn’t hurt.

I had crackers and hummus and ginger ale, and I haven’t wanted anything else to eat. My stomach feels different - not crampy or anything, just different.

I’m noticing that my head feels full and is low grade hurting. I’m quite tired.

Just wondering if anyone here got a headache post injection, or if I can (reasonably) attribute it to stress and visual migraine?

Thanks all.

I’m starting Mounjaro tomorrow (chose to start on Friday so that I have the weekend to deal with potential side effects).

The decision is solid.

And. I’m feeling very sad. I think I’m grieving for the me I am getting ready to change. From what I understand, some of the changes are expected, conscious. And some of them aren’t. Like, sure, maybe some GI issues. Or fatigue. Or maybe a suppression of desire.

And some of the changes are required and it means that I lose access to coping mechanisms that have been around for decades. That’s scary for me. Paying close attention to nutrition. Not gravitating to consuming food and drink as a reliable way to comfort and soothe. (I’m not saying it’s completely gone, just that it looks like it’s going to change dramatically.)

In fact, the whole not knowing how I will be, all the uncertainty - it’s tickling my depressive disorder.

It’s also got me feeling guarded. My mum is super excited about me going on this treatment. I understand, it’s coming from a loving place. And it’s triggering AF. I’m making all sorts of yucky connections between her excitement for potential benefits and her conditioning in diet culture.

I appreciate this forum - it’s helpful to just say the stuff. ❤️

I’m have done my research and have decided to go with Mounjaro.

Context: I’m 53F, some version of fat my entire adult life. Hashimoto’s, extensive osteoarthritis, fibromyalgia. I am also a smoker and I drink alcohol.

I’m paying for this out of pocket. It’s a big expense, AND…I am really hoping for benefits from this medicine - pain and inflammation reduction, the protective benefits around major organ disease, and maybe even impact on my tobacco and alcohol consumption. And honestly - I just want to feel free in my body.

What do I need to know as I start? What do you wish someone had told you?

Thanks community!!

Hi all - I don’t know if I chose the right flair for this question - mods, apologies if this isn’t correct.

I have been a smoker (with a three year gap) for decades. I want to quit.

I read that this class of drug impacts the desire centre of the brain, in addition to the GI impact and metabolic changes.

Have any of you had a shift in habits, like smoking or drinking?

Thank you for your input.

Hi all - I’m new here, a good friend recommended this board.

I have been some version of fat since 21 (53 F now). I manage major depressive disorder, Hashimoto’s disease, widespread osteoarthritis, and fibromyalgia. I have worked hard to find body neutrality and I am a firm advocate for HAES. I have been on the cusp of diabetes for a couple of years.

I have gone through all the bullshit yo-yo diet cycles, including eating keto for 3 years. I am a rule-following rebel and I am really resistant to restrictive eating.

In the past few years, my pain has increased significantly. I’m in a crappy cycle - when I exercise, I end up crippled for days, even when I’m careful. It is now really hard to manage stairs, and do my life. I’m having trouble standing for long stretches, and walking is no longer fun.

I live in Canada, and generic GLP1 has been approved here, likely released in the fall. I’m pretty sure it’s the Ozempic version, not sure if it includes Wegovy.

I have a restricted budget. My reading so far shows that Mounjaro is the best option, because it impacts inflammation, and because it has more options for dosage.

I am asking this community for help with deciding how to move forward. I have made the decision to start with a GLP1 medication. I’m trying to decide what one to take. I plan to be on this medication for the rest of my life, because the studies I have read show that the good effects reverse if the medication stops.

Has anyone started taking one and moved to another? Are there risks associated with doing that?

Thank you for sharing your experience.