[Spoilers] The fate of Sasuke
Since Ryu, Matsuri, and Mamushi are gone, Hidari is the next natural target before the story gets to Jura, and Sarada will likely be the one to take him out. But the problem is: the post-timeskip scene hints that both Naruto and Sasuke will stay out of the story until the very end. Since a Thorn Soul Bulb rots within minutes, it’s impossible to keep Sasuke benched that long without it killing him. The writer obviously can’t kill Sasuke off in such a pathetic way, so how do they keep him out of the story until the end?
The answer is Kawaki's timeless dimension. The moment Hidari is defeated, Kawaki could seal his Thorn Soul Bulb in his dimension where time doesn't flow, stopping it from rotting away. This lets Kawaki keep Sasuke locked up until the endgame, just like he did with Naruto. He has a few great reasons to do this, too: either to protect Sasuke because he knows how much he means to Naruto, or just to use the bulb as ultimate leverage against Boruto and Sarada.
The consequences: Jura would absolutely not let Hidari die, and try retrieving his Thorn Soul Bulb like he already did once before. That would make Kawaki one of his main targets alongside Boruto. This would lead to Boruto and Kawaki forming an even stronger alliance, because Boruto cannot let Kawaki die, or he'll lose both his parents and his master in the Daikokuten dimension forever. And Kawaki cannot let Boruto die, because he alone isn't strong enough to protect himself against Jura.