u/vkaranthkishi

Remission story

Hi everyone,

​I’m really just trying to understand what the path to remission actually looks like, and I’d love to hear from people who have made it to the other side.

​If you're in remission, what made the biggest difference for you? Was it a specific treatment adjustment, daily habits, or something else that felt like the real turning point?(vegetarian since birth btw)

​On a side note, I just need to vent a little. People keep giving advice like "just stay calm," "don't get angry," or "don't hold onto regret." I get that stress isn't great, but we're human! No one is walking around furious or stressed out 24/7—normal human emotions just happen once in a blue moon. Hearing people talk like emotional perfection is the magic cure leaves me so confused about what actually needs to change in daily life.

​If you've been through this, what real, practical steps actually helped?

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u/vkaranthkishi — 9 days ago

34F - High Grade p53 Abnormal EC - Surgery Tomorrow - Questions on Ovarian Sparing & Post-Op

​Hi everyone, I’m 34 years old and was diagnosed with Endometrial Cancer on March 11th. I’m looking for some insight or shared experiences as I’m actually admitted now and my surgery is tomorrow afternoon.

​My Situation:

Initially, my pathology suggested a lower-grade EC that was ER/PR and Vimentin positive. We were planning for fertility-sparing treatment. However, a second opinion at Mediclinic on the same slides changed everything: it’s been reclassified as High Grade p53 abnormal EC (ER/PR weakly negative, WT1 negative).

​Because of the high-grade p53 mutation, my doctors say fertility sparing is no longer an option and are recommending a total hysterectomy including the ovaries (BSO). My surgeon is checking with a team in France to see if we can potentially retain the ovaries for hormonal support, but they haven't checked my POLE status yet.

​I have a few questions for this community:

1)​Ovarian Sparing: Has anyone with high-grade p53 abnormal EC managed to spare their ovaries? If so, have you faced any complications or recurrences later on?

2)​Chemotherapy: For those with high-grade p53 mutations, did you require chemo/radiation after the surgery even if it was caught early?

3)​Last-minute Advice: Any suggestions or tips for someone literally sitting in the hospital bed awaiting surgery tomorrow?

4)​Final Assessments: I know it might sound delusional, but I’ve made lifestyle changes and I’m hoping for a miracle. Do surgeons perform a final assessment or "quick look" before proceeding with the full hysterectomy?

​I’m feeling a mix of emotions and still hoping for the best possible outcome. Please keep me in your thoughts/prayers. Thank you for listening to my story.

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u/vkaranthkishi — 4 months ago