u/whorificustotalus

Fat whores, rejoice! The 'Godzilla of weight-loss drugs' breaks records in phase 3 trial

Fat whores, rejoice! The 'Godzilla of weight-loss drugs' breaks records in phase 3 trial

So many happy ex-fatties on the horizon. We'll all be svelte when they start packing us onto trains.

>Retatrutide is a first-in-class "triple agonist" that targets receptors for three hormones – GLP-1, GIP, and glucagon – setting it apart from existing treatments like tirzepatide, which targets two.

>Those on 4mg of retatrutide lost 11.9% of their body weight on average, increasing to 16.8% with 9mg and 18.8% on 12mg. Among those on the 12 mg dose, almost half (47%) shed at least 20% of their starting weight and almost a third (31%) lost at least 25%.

>"It rivals gastric bypass surgery without the surgery," said Dr. Susan Spratt, an endocrinologist and senior medical director at Duke Health, who was not involved in the trial.

theguardian.com
u/whorificustotalus — 11 days ago