u/woooosel

Anyone start midodrine with normal blood pressure?

I was prescribed Midodrine a while back to help with suspected dysautonomia. I have all the hallmark symptoms, but my blood pressure is normal (it ranges from 100/70-120/78 usually). However, my heart rate jumps about 40-60 beats when I stand for longer than five minutes, which has led to fainting episodes in the past.

I've been on the meds for three days (taking 2.5 mg/day), and it's already sending me into Stage 1 diastolic hypertension (106/82 - 119/89). Don't get me wrong, it's been great - I don't have dizziness, brain fog, fainting, or fatigue when I'm on it. It has been such a big relief, but the numbers are concerning me, even in the adjustment period. It's definitely not a desired effect.

I also do not know if I have hyperadrenergic POTS. I've been diagnosed with hEDS and MCAS, but since wait times are long for specialists, my doctor is pill-trialing my dysautonomia.

Can anyone who has normal blood pressure and is on Midodrine share their experiences?

I'll be discussing this with my doctor on the next appointment, but figured I'd ask.

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u/woooosel — 12 hours ago