u/wucsma

Compounded LDN innacurate dose?

I've been stable on 3.0mg LDN for a few weeks now. I get all my LDN from Belmar Pharmacy. Just wondering if any one can provide some insight or share their experience.

I was originally prescribed 4.5mg by my pain management doc. My pcp recommended titrating up by 0.5mg steps. I am going the titration route, and so I have a bottle of 0.5mgs, i also have a bottle of the 4.5mgs from the original prescription.

Typically I would take 6 of the 0.5mg pills for 3.0mg. As I am going to be staying on 3.0mg for a while, i thought i could take half of the 4.5mg and two of the 0.5mg for a total of 3.25mg. Thus not wasting the 4.5mgs. Titration was done only with the 0.5mg pills. I had no side effects after getting to around 2.0mg. And did not have any side effects going from 3.0mg to 3.25mg. after a few days on 3.25mg, my pain symptoms returned. Yesterday my doc recommended i go back to exactly 3.0mg, with the 6 pills.

After taking the 6 yesterday, I immediately felt some side effects, i.e dizziness and nausea. The headache from initial titration has also returned.

Based on what Im feeling I had the initial thought that the 4.5mg pills were the wrong dose, and could likely be 0.5mg as well. If i was actually taking 3.25mg, 'decreasing' to 3.0mg should cause all these side effects right?

Thank you in advanced! My head and stomach are killing me.

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u/wucsma — 1 day ago

Help finding 'sweet spot' dose

Hi all, I am looking for some help finding my sweet spot dose for LDN. It was prescribed for pain amplification syndrome / radiculopathy secondary to breaking my neck a decade or so ago. I started about 3 weeks ago at 0.5mg in the morning and have been increasing in 0.5mg steps every few days. First 2 weeks were brutal. Constant headache, random bouts of nausea, and lots of throwing up. Weirdest thing is the headaches would move to a new location every day or so, whereas i usually only get them on the left side.

To be honest, it didnt really feel like the headaches were getting worse or changing much with each dose increase up until I hit 3.0mg. After a day or so on 3.0mg, it felt like all my negative symptoms disappeared and my pain was significantly reduced. Cant really speak on the pain prior to this point as my headache was too severe to really notice anything. I've honestly stuck to 3.0mg for the past week as those side effects were pretty insane.

My question is should I just stay at 3.0mg? Should I continue increasing the dose? Before LDN (on nothing), I'd say pain would fluctuate anywhere from 3/10 up to 7-8/10, but generally more on the low end. While its only been a week, on LDN I barely notice the pain in the evenings, like a 0.5/10, so much so that its helped tremendously with sleep. Mornings I still feel some pain, especially the first few hours right after taking LDN. Can my pain improve further with a higher dose?

Thanks for reading / helping!

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u/wucsma — 7 days ago