r/CFSScience

“Conclusions

Tailored exercise did not outperform standard care in HRQoL and was associated with reduced upright time, while improvements in several secondary outcomes were observed in both groups. Heterogeneity supports an individualized approach to exercise, integrated with pharmacological and multimodal management strategies”

Another one we might’ve predicted: A Pots cohort that included many patients exhibiting PEM (measured through DSQ questionnaire) did not respond well to tailored exercise programs. Both objective outcome measures showed significant reductions which makes me very distrustful of their subjective “positive secondary measures” to boot.

Good data point to refer too though from now on I guess

Hannover Medical School, 992 people.

Among those with Long COVID in 2021 who returned in 2024, 77.4% still met criteria about 4 years after infection.

More than 95% were never hospitalized initially

The study tested microtesla magnetic therapy (MMT) as a treatment for cognitive problems in Long COVID.

Design: small randomized, sham-controlled, triple-blind pilot trial; 30 participants completed it (20 MMT, 10 sham). 15 minutes, twice weekly for 4 weeks, using a low-amplitude 27.12 MHz magnetic field.

Possible benefits: the MMT group showed larger improvements by week 8 in:

• working memory
• verbal learning/memory
• processing speed
• anxiety
• emotional well-being

But: the cognitive and most quality-of-life findings did not survive correction for multiple comparisons, and the key mixed-effects analyses generally did not show significant treatment × time interactions.

Bottom line: MMT looks feasible and apparently safe, with some intriguing signals of efficacy, but this study does not establish that MMT works for Long COVID cognitive impairment.

Personal opinion: I dont know what they hope to achieve with 15 minutes, twice weekly. Does not sound like much of anything.